Objective: To study females with exposure to dioxin at an elevated high risk of breast cancer.
Design: Systematic review of environmental epidemiology studies.
Data sources: Pudmed, Medline, Embase, Cochrane Library and CEPS were used. All data sources were searched from January 1990 to September 2009.
Data extraction and statistical analysis: In this study, we included four papers in the meta-analysis method. Relative risks or odds ratios appeared in each study were used to estimate the correlation between dioxin exposure and breast cancer. Using the traditional meta-analysis and a new meta-analysis method, we summarized the association between female exposure to the dioxin and the risk of the breast cancer.
Results: Four environmental epidemiology studies met the inclusion criteria. In this methods, the correlation between dioxin exposure and breast cancer is positive. Nevertheless, the traditional meta-analysis was not statistical significance and new meta-analysis method was.
Conclusions: These are no protection effect to suffer the breast cancer for women exposed to the dioxin pollution, and perhaps these are adverse effect.
