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請使用永久網址來引用或連結此文件:
http://ir.cmu.edu.tw/ir/handle/310903500/30280
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| 題名: | Adjunctive fluvoxamine inhibits clozapine-related weight gain and metabolic disturbances |
| 作者: | Lu, ML;Lane, HY;Lin, SK;Chen, KP;Chang, WH |
| 貢獻者: | 附設醫院精神醫學部;China Med Univ Hosp, Dept Psychiat, Taichung 404, Taiwan;Taipei Med Univ, Dept Psychiat, Wan Fang Hosp, Taipei, Taiwan;Taipei City Psychiat Ctr, Dept Adult Psychiat, Taipei, Taiwan;Tzu Chi Univ, Hualien, Taiwan;Dalin Tzu Chi Gen Hosp, Dept Psychiat, Hualien, Taiwan |
| 日期: | 2004 |
| 上傳時間: | 2010-09-24 14:52:28 (UTC+8) |
| 出版者: | PHYSICIANS POSTGRADUATE PRESS |
| 摘要: | Application of combining herbal medicine and biomedical material science to nerve regeneration is a new approach. In this study, we describe a novel use of purified genipin, which can be extracted from Gardenia jasminoides Ellis, fixing the gelatin to be an extracellular matrix for peripheral nerve regeneration. A 10-mm gap of rat sciatic nerve was created between the proximal and distal nerve stumps, which were sutured into silicone rubber tubes filled with either the genipin-fixed gelatin or collagen gel. Silicone rubber tubes filled with saline were used as controls. Six weeks after implantation, regeneration across the nerve gaps occurred in 80 and 90% of the animals from the groups of genipin-fixed gelatin and collagen, respectively, whereas only 30% in them control group. Large numbers of myelinated axons were also seen in the genipin-fixed gelatin (5104 +/- 3278) and the collagen groups (8063 +/- 1807). These findings indicated that the genipin-fixed gelatin could be an acceptable extracellular matrix for nerve regeneration. |
| 關聯: | JOURNAL OF CLINICAL PSYCHIATRY 65(6):766-771 |
| 顯示於類別: | [台中附設醫院] 期刊論文
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