Adjunctive fluvoxamine inhibits clozapine-related weight gain and metabolic disturbances

CMUR > China Medical University Hospital > Jurnal articles > Item 310903500/30280

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/30280

Title:	Adjunctive fluvoxamine inhibits clozapine-related weight gain and metabolic disturbances
Authors:	Lu, ML;Lane, HY;Lin, SK;Chen, KP;Chang, WH
Contributors:	附設醫院精神醫學部;China Med Univ Hosp, Dept Psychiat, Taichung 404, Taiwan;Taipei Med Univ, Dept Psychiat, Wan Fang Hosp, Taipei, Taiwan;Taipei City Psychiat Ctr, Dept Adult Psychiat, Taipei, Taiwan;Tzu Chi Univ, Hualien, Taiwan;Dalin Tzu Chi Gen Hosp, Dept Psychiat, Hualien, Taiwan
Date:	2004
Issue Date:	2010-09-24 14:52:28 (UTC+8)
Publisher:	PHYSICIANS POSTGRADUATE PRESS
Abstract:	Application of combining herbal medicine and biomedical material science to nerve regeneration is a new approach. In this study, we describe a novel use of purified genipin, which can be extracted from Gardenia jasminoides Ellis, fixing the gelatin to be an extracellular matrix for peripheral nerve regeneration. A 10-mm gap of rat sciatic nerve was created between the proximal and distal nerve stumps, which were sutured into silicone rubber tubes filled with either the genipin-fixed gelatin or collagen gel. Silicone rubber tubes filled with saline were used as controls. Six weeks after implantation, regeneration across the nerve gaps occurred in 80 and 90% of the animals from the groups of genipin-fixed gelatin and collagen, respectively, whereas only 30% in them control group. Large numbers of myelinated axons were also seen in the genipin-fixed gelatin (5104 +/- 3278) and the collagen groups (8063 +/- 1807). These findings indicated that the genipin-fixed gelatin could be an acceptable extracellular matrix for nerve regeneration.
Relation:	JOURNAL OF CLINICAL PSYCHIATRY 65(6):766-771
Appears in Collections:	[China Medical University Hospital] Jurnal articles

Files in This Item:

There are no files associated with this item.

Loading...