Antioxidant activity and constituents of extracts from the root of Garcinia multiflora

CMUR > College of Pharmacy > Graduate Institute of Chinese Pharmaceutical Science > Journal articles > Item 310903500/7336

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/7336

Title:	Antioxidant activity and constituents of extracts from the root of Garcinia multiflora
Authors:	(Jyh-Horng Wu);(Yu-Tang Tung);(Chiou-Fung Chyu);(Shih-Chang Chien);(Sheng-Yang Wang);(Shang-Tzen Chang);郭悅雄*
Contributors:	藥學院中國藥學研究所;中國附醫院長室
Keywords:	Antioxidant;Bioactivity-guided isolation;Garcinia multiflora;Phytocompound;Reactive oxygen species
Date:	2008-06
Issue Date:	2009-08-26 16:20:25 (UTC+8)
Abstract:	The methanolic extract of the root of Garcinia multiflora and its derived soluble fractions, namely those soluble in ethyl acetate (EtOAc), n-butanol, and water, were screened for their antioxidant activities. Among them, the EtOAc-soluble fraction exhibited the highest scavenging activity against the 1,1-dipheny1,2-picrylhydrazyl radical, the highest superoxide radical scavenging activity, and the strongest reducing power. In addition, according to the bioactivity-guided isolation, 26 specific phytocompounds, including 3 aromatics, 3 benzophenones, 3 flavonoids, 3 isocoumarins, 1 phloroglucinol, 6 steroids, and 7 xanthones, were isolated from the EtOAc-soluble fraction and identified. Of these, 2,4,3′,4′-tetrahydroxy-6-methoxybenzophenone and 1,3,6,7-tetrahydroxyxanthone were found to be the major bioactive constituents, present in the crude extract in concentrations of 3.9 and 15.6 mg/g, respectively. These two compounds had similar antioxidant activities to (+)-catechin, a well-known antioxidant.
Relation:	JOURNAL OF WOOD SCIENCE 54(5)383~389
Appears in Collections:	[Graduate Institute of Chinese Pharmaceutical Science] Journal articles

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	503	View/Open

Loading...