Antioxidant activity and constituents of extracts from the root of Garcinia multiflora

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 藥學院 > 中國藥學研究所(已停用) > 期刊論文 > Item 310903500/7336

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題名:	Antioxidant activity and constituents of extracts from the root of Garcinia multiflora
作者:	(Jyh-Horng Wu);(Yu-Tang Tung);(Chiou-Fung Chyu);(Shih-Chang Chien);(Sheng-Yang Wang);(Shang-Tzen Chang);郭悅雄*
貢獻者:	藥學院中國藥學研究所;中國附醫院長室
關鍵詞:	Antioxidant;Bioactivity-guided isolation;Garcinia multiflora;Phytocompound;Reactive oxygen species
日期:	2008-06
上傳時間:	2009-08-26 16:20:25 (UTC+8)
摘要:	The methanolic extract of the root of Garcinia multiflora and its derived soluble fractions, namely those soluble in ethyl acetate (EtOAc), n-butanol, and water, were screened for their antioxidant activities. Among them, the EtOAc-soluble fraction exhibited the highest scavenging activity against the 1,1-dipheny1,2-picrylhydrazyl radical, the highest superoxide radical scavenging activity, and the strongest reducing power. In addition, according to the bioactivity-guided isolation, 26 specific phytocompounds, including 3 aromatics, 3 benzophenones, 3 flavonoids, 3 isocoumarins, 1 phloroglucinol, 6 steroids, and 7 xanthones, were isolated from the EtOAc-soluble fraction and identified. Of these, 2,4,3′,4′-tetrahydroxy-6-methoxybenzophenone and 1,3,6,7-tetrahydroxyxanthone were found to be the major bioactive constituents, present in the crude extract in concentrations of 3.9 and 15.6 mg/g, respectively. These two compounds had similar antioxidant activities to (+)-catechin, a well-known antioxidant.
關聯:	JOURNAL OF WOOD SCIENCE 54(5)383~389
顯示於類別:	[中國藥學研究所(已停用)] 期刊論文

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