本論文研究使用α-iodo-N-arylacetamides和formamide，成功簡易合成出N-arylformamide類化合物。本方法可適用於含有推、拉電子基團的α-iodo-N-arylacetamides，包含N-(benzo[1,3-d]dioxol-5-yl)-2-iodoacetamide、2-iodo-N-(pyridin-2-yl)acetamide、和2-iodo-N-(naphthalen-1-yl)acetamide，其合成產率約65–94%。並報告相關反應機轉以說明其反應進行過程。
A convenient synthetic method for N-arylformamide derivatives was successfully developed by reacting α-iodo-N-arylacetamides with formamide. This method was applicable to α-iodo-N-arylacetamide substrates bearing electron-donating or electron-withdrawing groups, N-(benzo[1,3-d]dioxol-5-yl)-2-iodoacetamide, 2-iodo-N-(pyridin-2-yl)acetamide, and 2-iodo-N-(naphthalen-1-yl)acetamide to give the corresponding N-arylformamides in moderate to excellent yields. A plausible mechanism was proposed to account for the new transformation.
