A convenient and efficient microwave-assisted amidination were developed by reacting various primary amines including aromatic amines and pyrazol-5-amines with amide solvents and POCl3 coupling agent. Our results suggested that yielding formylation amidinyl pyrazole products might seem determinate by the dissociation of the substituting amides by means of the steric and electronic effect of the substitutents on the amides.
