耳穴貼壓降低青光眼病患眼壓之效果：先導型單盲隨機臨床試驗

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题名:	耳穴貼壓降低青光眼病患眼壓之效果：先導型單盲隨機臨床試驗 Intraocular Pressure-Lowering Effect of Auricular Acupressure in Patients with Glaucoma: A Prospective Single-Blinded Randomized Controlled Trial
作者:	何建賢;Jiann-Shyan Her
贡献者:	中醫學院中西醫結合研究所碩士班
关键词:	耳穴貼壓;傳統(替補)醫學;青光眼;眼壓;視力;auricular acupressure;complementary and alternative medicine;glaucoma;intraocular pressure;visual acuity
日期:	2010
上传时间:	2010-09-29 11:57:42 (UTC+8)
摘要:	中文摘要論文題目：耳穴貼壓降低青光眼病患眼壓之效果：先導型單盲隨機臨床試驗。研究所名稱：中國醫藥大學中西醫結合研究所作者姓名：何建賢指導教授：陳永祥博士、陳汶吉博士背景與目的：本篇研究的主要目的在探討耳穴貼壓治療，在青光眼病人的眼壓控制效果。材料與方法：經由青光眼臨床門診總共收集33例青光眼病患。這些病患隨機分成耳穴貼壓組(16位病患，28隻青光眼患眼)及偽穴對照組(17位病患，32隻青光眼患眼)。耳穴貼壓組接受耳穴(腎、肝、眼)耳珠貼布刺激及為期四周每天兩次的規則按摩。偽穴對照組僅在耳穴(腕、肩、下頜)接受耳珠貼布刺激而不進行按摩。針對眼壓及視力我們在治療四週後及門診追蹤至八週時，進行治療前後比較評估。結果：經過試驗性治療及八週的追蹤後，耳穴貼壓組與治療前相較眼壓及視力得到明顯的改善(P<0.05)。最明顯的眼壓降低效果發生在耳穴貼壓治療後的三至四週，眼壓在治療終止四週後，回升至初始治療的水平。在耳穴貼壓組中未矯正視力於治療期間二至四週中，可得到明顯的改善，同樣的在偽穴對照組中，我們也可觀察到視力有改善的跡象，但只有在治療第三週與治療前有明顯的差異。最佳矯正視力在兩組中均有改善跡象，但唯有耳穴貼壓組在第二週與治療前相比出現明顯差異。結論：對於青光眼病患，我們的資料顯示耳穴貼壓，可以做為一種替補治療的方式來改善眼壓及視力。 Abstract Background: The objective of the study was to evaluate the effect of auricular acupressure in controlling the intraocular pressure (IOP) in glaucoma patients. Methods: Thirty-three patients were recruited through advertisement at the clinic for glaucoma. These patients were divided into the auricular acupressure group (16 patients, 28 glaucoma eyes) and the sham group (17 patients, 32 glaucoma eyes). Patients in the acupressure group received auricular acupoint (kidney, liver, and eye) stimulator tapping and regular massage twice a day for 4 weeks. Patients in the sham group received tapping at sham auricular acupoints (wrist, shoulder, and jaw) without massage stimulation. The IOP and visual acuity (VA) were assessed before and after the treatment in the first 4 weeks and followed up, up to 8 weeks. Results: After the treatment and at the 8-week follow-up, IOP and VA improved significantly in the acupressure group when compared with pre-treatment (P<0.05). The most significant IOP-lowering effect was seen at about 3 to 4 weeks after auricular acupressure. IOP returned to the initial level after acupressure had been discontinued for 4 weeks. Significant improvement of the uncorrected VA (UCVA) was noted at about 2 to 4 weeks in the acupressure group. UCVA improvement was also noted in the sham group. The difference was only significant in week 3. Improvement of the best-corrected VA was noted in both groups, but was only significant at the acupressure group in week 2. Conclusions: Our data suggest that auricular acupressure can be used as a complementary treatment to ameliorate IOP and VA for patients with glaucoma.
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