脈診儀在精神疾病患者脈波之研究

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題名:	脈診儀在精神疾病患者脈波之研究 Study of Psychotic disorder by the Pulse Spectrum Analysis
作者:	王鴻松;Hong-Song Wang
貢獻者:	中醫學院中西醫結合研究所碩士班
關鍵詞:	脈診;精神疾病;躁鬱症;精神分裂症;Pulse Spectrum Analysis;psychosis;bipolar disorder;schizophrenia
日期:	2010
上傳時間:	2010-09-29 11:57:34 (UTC+8)
摘要:	精神分裂症和躁鬱症是精神科中較嚴重且需要長期治療的疾病。病人多在年輕時發病，影響到病人的生活品質。根據文獻回溯，我們發現精神分裂症和躁鬱症的病人在分子基礎的表現都與正常人不同。中醫典籍中也指出精神分裂症和躁鬱症的病人體質異於常人。所以如果能以科學的方法，來辨識精神分裂症和躁鬱症的患者，在診斷與追蹤精神分裂症和躁鬱症的病人，將有相當的助益。本研究的目的，是利用脈診儀(台灣科隆公司PDS-2000電腦脈波分析系統)來分析精神分裂症和躁鬱症的患者與亞健康者的橈動脈脈波，利用傅立葉轉換成頻譜諧波，依此計算出每個受試者各共振諧波的相關測量值，參考王唯工教授的共振假說，再進一步比較精神分裂症和躁鬱症的患者與亞健康者在脈搏諧波測量值上的差異。本研究收集了 30位精神分裂症患者、30位躁鬱症患者與30位無精神疾病的亞健康志願者。以ANOVA(p<0.05)分析後發現，在精神分裂症組與亞健康組之間，C3(脾經)與C5(胃經)的脈搏諧波測量值有統計上的差異(ｐ<0.05)，且左右手皆有類似的結果；以各諧波百分比來分析時，發現左右手的C3(脾經)與C5(胃經)諧波百分比沒有統計上的差異(P>0.05)。在躁鬱症組與亞健康組之間，C3(脾經)的脈搏諧波測量值有統計上的差異(ｐ<0.05)，且左右手皆有類似的結果；當我們以各諧波百分比來分析時，也發現左右手的C3(脾經)諧波百分比有統計上的差異(P<0.05)。脈診儀的科學性與客觀性，在臨床上是個很好的非侵犯性診斷工具，今後如果我們能多做進一步的研究，能簡化整個操作流程，對相關疾病的診斷與預後，可以提供很好的輔助功能。 In psychiatry, schizophrenia and bipolar disorder are more severe diseases and need long term treatment. The patients have these diseases at the young age and their life quality is influenced. Literatures indicate that the molecular basis of patients with schizophrenia and bipolar disorder are different from that of healthy individuals. According to the classics of traditional Chinese medicine, the body constitution of patients with schizophrenia and bipolar disorder is also different from that of healthy individuals. If we can recognize patients with schizophrenia and bipolar disorder by means of scientific methods, it will improve the diagnosis and follow-up. The purpose of this study is to determine the differences in pulse spectrum analysis between patients with schizophrenia and bipolar disorder and non-psychotic healthy individuals. A pulse spectrum analyzer (SKYLARK PDS-2000 Pulse Analysis System) was used to measure radial arterial pulse waves of subjects. Original data was then transformed to spectrum data by Fourier transformation. The relative strength of each harmonic wave was calculated according to Professor Wang Wei-Kung’s theory. We then compared and contrasted the harmonic values between patients with schizophrenia and bipolar disorder and non-psychotic healthy individuals. In total, ninety participants, thirty with schizophrenia, thirty with bipolar disorder and thirty with non-psychotic healthy individuals participated in the study. By ANOVA analysis, harmonic values of C3 (Spleen Meridian) and C5 (Stomach Meridian) were significantly different (p<0.05) between the schizophrenia group and the non-psychotic healthy group. The results derived from two hands are similar. The harmonic percentage of C3 (Spleen Meridian) and C5 (Stomach Meridian) was not significantly different (p<0.05) between the two groups. Harmonic values of C3 (Spleen Meridian) was significantly different (p<0.05) between the bipolar disorder group and the non-psychotic healthy group. The results derived from two hands are similar. The harmonic percentage of C3 (Spleen Meridian) was significantly different (p<0.05) between the two groups. The pulse spectrum analyzer is an excellent non-invasive diagnostic tool to make scientific and objective diagnosis. If we can study more in this field and simplify the procedure, we will reach a greatly improvement in diagnosis and prognosis of diseases.
顯示於類別:	[中西醫結合研究所] 博碩士論文

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