The signal transduction mechanism involved in kazinol B-stimulated superoxide anion generation in rat neutrophils

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 藥學院 > 藥物化學研究所 > 期刊論文 > Item 310903500/30940

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题名:	The signal transduction mechanism involved in kazinol B-stimulated superoxide anion generation in rat neutrophils
作者:	Wang, JP;Tsao, LT;Raung, SL;Lin, CN
贡献者:	藥學院藥化所;Taichung Vet Gen Hosp, Dept Med Res, Taichung 407, Taiwan;China Med Coll, Grad Inst Pharmaceut Chem, Taichung, Taiwan;Kaohsiung Med Coll, Sch Pharm, Kaohsiung, Taiwan
日期:	1998
上传时间:	2010-09-24 15:07:02 (UTC+8)
出版者:	STOCKTON PRESS
摘要:	The effect of Jen-San-Yaung-Jung-Tang (YJT) on scopolamine (SCOP)-induced amnesia was investigated in a step-through passive avoidance task in rats. It was observed that YJT (0.5 and 1.0 g/kg) significantly improved SCOP-induced amnesia and did not change the horizontal activity and pain threshold. YJT at 0.5 and 1.0 g/kg also did not change SCOP-treated horizontal activity and pain threshold. Furthermore, the antiamnesic effect of YJT at 1.0 g/kg on the SCOP-induced amnesia was augmented by physostigmine, but was not altered by neostigmine or scopolamine N-methylbromide. These results suggest that the antiamnesic effect of YJT could only be related to the memory-related process, and to an increase in central cholinergic neuronal activity.
關聯:	BRITISH JOURNAL OF PHARMACOLOGY 125(3):517-525
显示于类别:	[藥物化學研究所] 期刊論文

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