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    題名: Effect of long-term administration of berberine on scopolamine-induced amnesia in rats
    作者: Peng, WH;Hsieh, MT;Wu, CR
    貢獻者: 藥學院中藥所;Peng, WH, CHINA MED COLL,INST CHINESE PHARMACEUT SCI,91 HSUEH SHIH RD,TAICHUNG,TAIWAN
    日期: 1997
    上傳時間: 2010-09-24 14:58:36 (UTC+8)
    出版者: JAPANESE PHARMACOLOGICAL SOC
    摘要: Technetium-99m-tetrofosmin has emerged as a new radiopharmaceutical for myocardial imaging, in competition with Tl-201 and Tc-99m-MlBI. In this study, Tc-99m-tetrofosmin was evaluated for its ability to detect malignant and benign lesions from single solid lung masses. Methods: Forty-nine patients with a single solid lung mass based on chest radiograph findings received Tc-99m-tetrofosmin SPECT of the chest to evaluate the value of Tc-99m-tetrofosmin SPECT for detecting malignant and benign lesions. Results: Only 61% of the lung malignancies were detected by Tc-99m-tetrofosmin SPECT of the chest, including 53% of epidermoid carcinoma (ca), 67% of adeno ca, 75% of small-cell ca, 0% of undifferentiated large-cell ca and 100% of other lung malignancies. In addition, 50% of the benign lesions were detected by chest Tc-99m-tetrofosmin SPECT. The probability of tetrofosmin uptake in the mass was not related to mass size. The diagnostic sensitivity, specificity and accuracy were 61%, 50% and 59%, respectively, for differentiating malignant and benign lesions when diagnosing a single solid lung mass. Conclusion: Technetium-99m-tetrofosmin SPECT of the chest is of little or no value for the detection of lung ca from single solid lung masses.
    關聯: JAPANESE JOURNAL OF PHARMACOLOGY 74(3):261-266
    顯示於類別:[中國藥學研究所(已停用)] 期刊論文

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