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    題名: Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38
    作者: Yang, JS;Hour, MJ;Kuo, SC;Huang, LJ;Lee, MR
    貢獻者: 醫學院醫學系生化學科;China Med Univ, Sch Med, Dept Biochem, Taichung 404, Taiwan;China Med Univ, Grad Inst Pharmaceut Chem, Taichung 404, Taiwan;China Med Univ, Sch Pharm, Taichung 404, Taiwan
    日期: 2004
    上傳時間: 2010-09-24 14:54:45 (UTC+8)
    出版者: INT INST ANTICANCER RESEARCH
    摘要: The aim of this study was (1) to investigate the correlation between external exposure to N,N-dimethylformamide (DAY) and urinary excretion of DMF and N-methylformamide; (2) to assess whether the correspondence between the current occupational exposure limit setting and recommended urinary biological exposure index is substantial; and (3) to evaluate whether coexposure to toluene, methyl ethyl ketone, and ethyl acetate has an effect on urinary excretion of DAY and N-methylformamide (MMF). Urinary DAY and NAY were significantly correlated (P < 0.01) with one another and also significantly correlated with airborne DMF (P < 0.01) over the range of 1.55 to 152.8 mg/m(3). Urinary DAY can be considered a complementary marker for short-term exposure. Urinary concentration of NAY, and DMF, corresponding to the 8-hour exposure to airborne DAY at 30 mg/m(3) was estimated to 38.4 mg/L or 39.4 mg/g creatinine for NW and to 0.92 mg/L or 0.96 mg/g creatinine for DMF.
    關聯: ANTICANCER RESEARCH 24(3A):1769-1778
    顯示於類別:[醫學系] 期刊論文

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