Expanded trinucleotide repeats in the TBP/SCA17 gene mapped to chromosome 6q27 are associated with schizophrenia

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/30298

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.cmu.edu.tw/ir/handle/310903500/30298

题名:	Expanded trinucleotide repeats in the TBP/SCA17 gene mapped to chromosome 6q27 are associated with schizophrenia
作者:	Chen, CM;Lane, HY;Wu, YR;Ro, LS;Chen, FL;Hung, WL;Hou, YT;Lin, CY;Huang, SY;Chen, IC;Soong, BW;Li, ML;Hsieh-Li, HM;Su, MT;Lee-Chen, GJ
贡献者:	附設醫院精神醫學部;China Med Univ Hosp, Dept Psychiat, Taichung 404, Taiwan;Chang Gung Univ, Coll Med, Taipei 105, Taiwan;Chang Gung Mem Hosp, Dept Neurol, Taipei 105, Taiwan;Natl Taiwan Normal Univ, Dept Life Sci, Taipei 116, Taiwan;Taipei Vet Gen Hosp, Neurol Inst, Taipei 112, Taiwan;Natl Yang Ming Univ, Sch Med, Taipei 112, Taiwan
日期:	2005
上传时间:	2010-09-24 14:52:48 (UTC+8)
出版者:	ELSEVIER SCIENCE BV
摘要:	The aim of this study was to examine whether -627 interleukin-10 (IL-10) promoter polymorphism is a marker of susceptibility to or severity of rheumatoid arthritis (RA) in Chinese patients in Taiwan. The study included 198 Chinese patients with RA. One hundred unrelated healthy individuals living in central Taiwan served as the control subjects. The relationship between IL-10 gene polymorphism and clinical manifestations of RA was evaluated. For the genotype, allelic frequency, and carriage rate of IL-10 polymorphism, there were no statistically significant differences found between patients and controls. Furthermore, we did not detect any association of IL-10 genotype with rheumatoid factor (RF), extra-articular involvement, or bone erosion in the RA patients. The lack of association of -627 IL-10 gene polymorphism with RA and the clinical findings in our study implies that the IL-10 gene polymorphism cannot serve as a candidate gene marker for screening RA patients.
關聯:	SCHIZOPHRENIA RESEARCH 78(2月3日):131-136
显示于类别:	[台中附設醫院] 期刊論文

文件中的档案:

没有与此文件相关的档案.

在CMUR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....