Rapid screening assay of congenital adrenal hyperplasia by measuring 17 alpha-hydroxyprogesterone with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry from dried blood spots

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29924

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.cmu.edu.tw/ir/handle/310903500/29924

题名:	Rapid screening assay of congenital adrenal hyperplasia by measuring 17 alpha-hydroxyprogesterone with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry from dried blood spots
作者:	Lai, CC;Tsai, CH;Tsai, FJ;Wu, JY;Lin, WD;Lee, CC
贡献者:	附設醫院基因醫學部;China Med Coll Hosp, Dept Med Genet & Med Res, Taichung 404, Taiwan
日期:	2002
上传时间:	2010-09-24 14:45:41 (UTC+8)
出版者:	WILEY-LISS
摘要:	Objective: To evaluate the association between endometriosis and the p53 polymorphism. Design: Prospective study. Setting: Department of gynecology and genetics in a medical center. Patient(s): Women with and without endometriosis. Intervention(s): Women were categorized as having moderate or severe endometriosis (n = 118) or no endometriosis (n = 140). Main Outcome Measure(s): Polymerase chain reaction was used to detect p53 codon 72 polymorphisms (arginine homozygosity, heterozygosity, and proline homozygosity). Associations between endometriosis and p53 polymorphisms were evaluated. Result(s): The distributions of different p53 polymorphisms differed significantly between groups. The respective proportions of arginine homozygotes, heterozygotes, and proline homozygotes were 10.2%, 66.9%, and 22.9% in the group with endometriosis and 30.7%, 50%, and 19.3% in the group without endometriosis. Conclusion(s): Endometriosis is associated with p53 polymorphism, p53 arginine homozygotes have lower risk for endometriosis. Heterozygotes and proline homozygotes have higher risk for endometriosis. (Fertil Steril(R) 2002;77:43-5. (C) 2002 by American Society for Reproductive Medicine.).
關聯:	JOURNAL OF CLINICAL LABORATORY ANALYSIS 16(1):20-25
显示于类别:	[台中附設醫院] 期刊論文

文件中的档案:

没有与此文件相关的档案.

在CMUR中所有的数据项都受到原著作权保护.

TAIR相关文章

数据加载中.....