中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/29666
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    題名: Simultaneously evaluating the effects of one-week fluticasone propionate inhalation therapy on lung ventilation and permeability in children with asthma
    作者: Chen, AC;Tsai, FJ;Tsai, CH;Lin, CC;Lee, CC;Kao, CH
    貢獻者: 附設醫院核子醫學部;China Med Univ Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Univ Hosp, Dept Pediat, Taichung 404, Taiwan;China Med Univ Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Univ Hosp, Dept Med Res, Taichung 404, Taiwan
    日期: 2003
    上傳時間: 2010-09-24 14:39:58 (UTC+8)
    出版者: SPRINGER-VERLAG
    摘要: Three new [n-pentyl beta-carboline-1-propionate (1), 5-hydroxymethyl-9-methoxycanthin-6-one (2), and 1-hydroxy-9-methoxycanthin-6-one (3)] and 19 known beta-carboline alkaloids were isolated from the roots of Eurycoma longifolia. The new structures were determined by comprehensive analyses of their 1D and 2D NMR and mass spectral data and by chemical transformation. These compounds were screened for in vitro cytotoxic and antimalarial activities, and 9-methoxycanthin-6-one (4) and canthin-6-one (5) demonstrated significant cytotoxicity against human lung cancer (A-549) and human breast cancer (MCF-7) cell lines.
    關聯: LUNG 181(5):283-289
    顯示於類別:[台中附設醫院] 期刊論文

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