Simultaneously evaluating the effects of one-week fluticasone propionate inhalation therapy on lung ventilation and permeability in children with asthma

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Title:	Simultaneously evaluating the effects of one-week fluticasone propionate inhalation therapy on lung ventilation and permeability in children with asthma
Authors:	Chen, AC;Tsai, FJ;Tsai, CH;Lin, CC;Lee, CC;Kao, CH
Contributors:	附設醫院核子醫學部;China Med Univ Hosp, Dept Nucl Med, Taichung 404, Taiwan;China Med Univ Hosp, Dept Pediat, Taichung 404, Taiwan;China Med Univ Hosp, Dept Family Med, Taichung 404, Taiwan;China Med Univ Hosp, Dept Med Res, Taichung 404, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:39:58 (UTC+8)
Publisher:	SPRINGER-VERLAG
Abstract:	Three new [n-pentyl beta-carboline-1-propionate (1), 5-hydroxymethyl-9-methoxycanthin-6-one (2), and 1-hydroxy-9-methoxycanthin-6-one (3)] and 19 known beta-carboline alkaloids were isolated from the roots of Eurycoma longifolia. The new structures were determined by comprehensive analyses of their 1D and 2D NMR and mass spectral data and by chemical transformation. These compounds were screened for in vitro cytotoxic and antimalarial activities, and 9-methoxycanthin-6-one (4) and canthin-6-one (5) demonstrated significant cytotoxicity against human lung cancer (A-549) and human breast cancer (MCF-7) cell lines.
Relation:	LUNG 181(5):283-289
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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