Correlation between P-glycoprotein (P-gp) expression in parathyroid and Tc-99m MIBI parathyroid image findings

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Title:	Correlation between P-glycoprotein (P-gp) expression in parathyroid and Tc-99m MIBI parathyroid image findings
Authors:	Sun, SS;Shiau, YC;Lin, CC;Kao, A;Lee, CC
Contributors:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung, Taiwan;Far Eastern Mem Hosp, Dept Nucl Med, Taipei, Taiwan;Natl Taiwan Univ, Coll Elect Engn, Inst Biomed Engn, Taipei, Taiwan
Date:	2001
Issue Date:	2010-09-24 14:36:01 (UTC+8)
Publisher:	ELSEVIER SCIENCE INC
Abstract:	Kang-chih-ma is the dried roots and stems of Helicteres angustifolia (Sterculiaceae) and a commonly used folk herbal drug in Taiwan. It possesses anti-dotal, analgesic, anti-inflammatory and anti-bacterial effects and is also known as a kind of tumor inhibitory plant. To evaluate the quality of H. angustifolia, a simple, rapid and accurate high-performance liquid chromatographic (HPLC) method was developed for the assay of three lupane type triterpenes: 3 beta -acetoxy-27-benzoyloxylup-20(29)-en-28-oic acid methyl ester (methyl helicterate), 3 beta -acetoxy-27-benzoyloxylup-20(29)-en-28-oic acid, and 3 beta -acetoxy-27-(p-hydroxyl) benzoyloxylup-20(29)-en-28-oic acid methyl ester. The present HPLC system used an Inertsil ODS-2 column by gradient elution with acetonitrile and water as the mobile phase and detected at UV 230 nm. Regression equations revealed good linear relationships (correlation coefficients: 0.9922-0.9997). The relative standard deviations of these three constituents ranged between 1.05-3.14% (intraday) and 2.12-4.38% (interday). The contents of these three constituents of the heartwood and the bark of the roots of H. angustifolia in five different samples have also been determined. (C) 2001 Elsevier Science B.V. All rights reserved.
Relation:	NUCLEAR MEDICINE AND BIOLOGY 28(8):929-933
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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