Correlation between P-glycoprotein (P-gp) expression in parathyroid and Tc-99m MIBI parathyroid image findings

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29495

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题名:	Correlation between P-glycoprotein (P-gp) expression in parathyroid and Tc-99m MIBI parathyroid image findings
作者:	Sun, SS;Shiau, YC;Lin, CC;Kao, A;Lee, CC
贡献者:	附設醫院核子醫學部;China Med Coll Hosp, Dept Nucl Med, Taichung, Taiwan;China Med Coll Hosp, Dept Family Med, Taichung, Taiwan;China Med Coll Hosp, Dept Med Res, Taichung, Taiwan;Far Eastern Mem Hosp, Dept Nucl Med, Taipei, Taiwan;Natl Taiwan Univ, Coll Elect Engn, Inst Biomed Engn, Taipei, Taiwan
日期:	2001
上传时间:	2010-09-24 14:36:01 (UTC+8)
出版者:	ELSEVIER SCIENCE INC
摘要:	Kang-chih-ma is the dried roots and stems of Helicteres angustifolia (Sterculiaceae) and a commonly used folk herbal drug in Taiwan. It possesses anti-dotal, analgesic, anti-inflammatory and anti-bacterial effects and is also known as a kind of tumor inhibitory plant. To evaluate the quality of H. angustifolia, a simple, rapid and accurate high-performance liquid chromatographic (HPLC) method was developed for the assay of three lupane type triterpenes: 3 beta -acetoxy-27-benzoyloxylup-20(29)-en-28-oic acid methyl ester (methyl helicterate), 3 beta -acetoxy-27-benzoyloxylup-20(29)-en-28-oic acid, and 3 beta -acetoxy-27-(p-hydroxyl) benzoyloxylup-20(29)-en-28-oic acid methyl ester. The present HPLC system used an Inertsil ODS-2 column by gradient elution with acetonitrile and water as the mobile phase and detected at UV 230 nm. Regression equations revealed good linear relationships (correlation coefficients: 0.9922-0.9997). The relative standard deviations of these three constituents ranged between 1.05-3.14% (intraday) and 2.12-4.38% (interday). The contents of these three constituents of the heartwood and the bark of the roots of H. angustifolia in five different samples have also been determined. (C) 2001 Elsevier Science B.V. All rights reserved.
關聯:	NUCLEAR MEDICINE AND BIOLOGY 28(8):929-933
显示于类别:	[台中附設醫院] 期刊論文

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