Ureteral fibroepithelial polyp prolapsed into the bladder cavity suspending a bladder stone

CMUR > China Medical University Hospital > Jurnal articles > Item 310903500/29336

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/29336

Title:	Ureteral fibroepithelial polyp prolapsed into the bladder cavity suspending a bladder stone
Authors:	Yeh, CC;Lin, HC;Chen, CC;Wu, HC
Contributors:	附設醫院泌尿部;China Med Coll Hosp, Dept Urol, Taichung, Taiwan
Date:	2001
Issue Date:	2010-09-24 14:32:32 (UTC+8)
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Abstract:	In this study, we attempted to identify the mechanisms of paeoniflorin on antinociceptive effects in mice. Paeoniflorin (48, 96, 240, 480 mug, i.c.v.) showed dose-related antinociception both on the early and late phases of formalin test in mice. Moreover, paeoniflorin (48 mug, i.c.v.) could potentiate the antinociception of morphrine (0.5, 1.0 mg/kg, s.c.) in the formalin test. However, the antinociceptive effects of paeoniflorin were not potentiated by L-arginine (600 mg/kg, i.p.) or antagonized by beta -funaltrexamine (beta -FNA) (10 mug, i.c.v.), ICI-174,864 (1 mug, i.c.v.) and ryanodine (10 ng, i.c.v.) on both the early and late phases of formalin test. L-NAME (75 mg/kg, i.p.) could reverse the effect of paeoniflorin on the late phase of formalin test. Naloxone (1 mg/kg, i.p.) and nor-binaltorphimine (nor-BNI) (1 mug, i.c.v.) could block the paeoniflorin-induced antinociception on the early phase of formalin test. These results suggested that the central antinociceptive effects of paeoniflorin on formalin test in mice were mediated by the activation of kappa -opioid receptor and not related to the increase of intracellular calcium. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.
Relation:	JOURNAL OF UROLOGY 165(5):1627-1628
Appears in Collections:	[China Medical University Hospital] Jurnal articles

Files in This Item:

There are no files associated with this item.

Loading...