Complications of Inoue balloon mitral commissurotomy: Impact of operator experience and evolving technique

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29028

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題名:	Complications of Inoue balloon mitral commissurotomy: Impact of operator experience and evolving technique
作者:	Hung, JS;Lau, KW;Lo, PH;Chern, MS;Wu, JJ
貢獻者:	附設醫院內科部心臟科;China Med Coll Hosp, Cardiol Sect, Taichung, Taiwan;Chang Gung Mem Hosp, Kaohsiung, Taiwan;Chang Gung Mem Hosp, Taipei 10591, Taiwan
日期:	1999
上傳時間:	2010-09-24 14:19:09 (UTC+8)
出版者:	MOSBY-YEAR BOOK INC
摘要:	PTEN/MMAC1, a potential human tumor suppressor gene, has been found to have inactivating mutations in several types of cancer, including breast cancer. The incidence of breast cancer in Chinese is quite low in comparison with Caucasians, and genetic factors may play some roles. To further determine the role of PTEN/MMAC1 in breast cancer in Chinese, we used loss of heterozygosity (LOH), single strand conformation polymorphism (SSCP) with direct sequencing of variant bands, and Southern blot analysis methods to analyze mutations in PTEN/MMAC1 in 52 cases of breast cancer. None had LOH at chromosome 10q23.3. One mutation was identified, a somatic 3-base deletion, in one case. Our results suggest PTEN/MMAC1 does not play a major role in the development of sporadic breast cancer.
關聯:	AMERICAN HEART JOURNAL 138(1):114-121
顯示於類別:	[台中附設醫院] 期刊論文

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