Complications of Inoue balloon mitral commissurotomy: Impact of operator experience and evolving technique

CMUR > China Medical University Hospital > Jurnal articles > Item 310903500/29028

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/29028

Title:	Complications of Inoue balloon mitral commissurotomy: Impact of operator experience and evolving technique
Authors:	Hung, JS;Lau, KW;Lo, PH;Chern, MS;Wu, JJ
Contributors:	附設醫院內科部心臟科;China Med Coll Hosp, Cardiol Sect, Taichung, Taiwan;Chang Gung Mem Hosp, Kaohsiung, Taiwan;Chang Gung Mem Hosp, Taipei 10591, Taiwan
Date:	1999
Issue Date:	2010-09-24 14:19:09 (UTC+8)
Publisher:	MOSBY-YEAR BOOK INC
Abstract:	PTEN/MMAC1, a potential human tumor suppressor gene, has been found to have inactivating mutations in several types of cancer, including breast cancer. The incidence of breast cancer in Chinese is quite low in comparison with Caucasians, and genetic factors may play some roles. To further determine the role of PTEN/MMAC1 in breast cancer in Chinese, we used loss of heterozygosity (LOH), single strand conformation polymorphism (SSCP) with direct sequencing of variant bands, and Southern blot analysis methods to analyze mutations in PTEN/MMAC1 in 52 cases of breast cancer. None had LOH at chromosome 10q23.3. One mutation was identified, a somatic 3-base deletion, in one case. Our results suggest PTEN/MMAC1 does not play a major role in the development of sporadic breast cancer.
Relation:	AMERICAN HEART JOURNAL 138(1):114-121
Appears in Collections:	[China Medical University Hospital] Jurnal articles

Files in This Item:

There are no files associated with this item.