Accuracy of three diagnostic tests used alone and in combination for detecting Helicobacter pylori infection in patients with bleeding gastric ulcers

CMUR > College of Medicine > School of Medicine > Journal articles > Item 310903500/30166

Please use this identifier to cite or link to this item: http://ir.cmu.edu.tw/ir/handle/310903500/30166

Title:	Accuracy of three diagnostic tests used alone and in combination for detecting Helicobacter pylori infection in patients with bleeding gastric ulcers
Authors:	Liao, CC;Lee, CL;Lai, YC;Huang, SH;Lee, SC;Wu, CH;Tu, TC;Chen, TK;Bai, CH
Contributors:	醫學院醫學系;Cathay Gen Hosp, Div Gastroenterol, Dept Internal Med, Taipei 106, Taiwan;Cathay Gen Hosp, Div Pathol, Taipei 106, Taiwan;China Med Univ, Sch Med, Taichung 400, Taiwan;Taipei Med Univ, Sch Med, Taipei 222, Taiwan;Inst Nucl Energy Res, Taoyuan 300, Taiwan;Acad Sinica, Dept Epidemiol, Inst Biomed Sci, Taipei 106, Taiwan
Date:	2003
Issue Date:	2010-09-24 14:50:26 (UTC+8)
Publisher:	CHINESE MEDICAL ASSOCIATION
Abstract:	The aim of this study was to investigate the effect of electrical stimulation on activator protein-1 (AP-1) in recombinant liver cells. In order to elucidate the molecular effects of electrical stimulation on cells, AP-1 expression was detected by a luciferase assay. The parameters used were taken from clinical electroacupuncture (EA) therapy as follows: biphasic rectangular symmetrical pulses (frequency: 2, 10 and 100 Hz; pulse width: 50, 80, 130 and 250 musec; intensity: 1, 2, 5 and 10 mA; time: 5, 10, 20 and 30 minutes). S (10% fetal bovine serum in medium), SF(serum free medium) and 12-O-tetradecanoylphorbol-13-acetate (TPA) treatment represented the experimental, negative and positive groups, respectively. We found that electrical stimulation with 10 Hz, a pulse width of 130 musec, and a duration of 30 minutes gave a significant increase in AP-1 activity. In contrast, the intensity of the stimulation had no significant effect on AP-1 activity. In conclusion, our data suggest that electrical stimulation with an appropriate frequency, duration and pulse width could cause an increase in AP-1 activity in cells.
Relation:	CHINESE MEDICAL JOURNAL 116(12):1821-1826
Appears in Collections:	[School of Medicine] Journal articles

Files in This Item:

There are no files associated with this item.

Loading...