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請使用永久網址來引用或連結此文件:
http://ir.cmu.edu.tw/ir/handle/310903500/29123
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| 題名: | Breast cancer diagnosis using three-dimensional ultrasound and pixel relation analysis |
| 作者: | Chen, WM;Chang, RF;Moon, WK;Chen, DR |
| 貢獻者: | 附設醫院外科部;China Med Coll & Hosp, Dept Gen Surg, Taichung, Taiwan;Natl Chung Cheng Univ, Dept Comp Sci & Informat Engn, Chiayi, Taiwan;Seoul Natl Univ Hosp, Dept Diagnost Radiol, Seoul 110744, South Korea |
| 日期: | 2003 |
| 上傳時間: | 2010-09-24 14:22:46 (UTC+8) |
| 出版者: | ELSEVIER SCIENCE INC |
| 摘要: | Aims: To investigate the concentration of urinary 8-hydroxydeoxyguanosine (8-OHdG) among electroplating workers in Taiwan. Methods: Fifty workers were selected from five chromium (Cr) electroplating plants in central Taiwan. The 20 control subjects were office workers with no previous exposure to Cr. Urinary 8-OHdG concentrations were determined using high performance liquid chromatography with electrochemical detection. Results: Urinary 8-OHdG concentrations among Cr workers (1149.5 pmol/kg/day) were higher than those in the control group (730.2 pmol/kg/day). There was a positive correlation between urinary 8-OHdG concentrations and urinary Cr concentration (r = 0.447, p < 0.01), and urinary 8-OHdG correlated positively with airborne Cr concentration (r = 0.285). Using multiple regression analysis, the factors that affected urinary 8-OHdG concentrations were alcohol, the common cold, and high urinary Cr concentration. There was a high correlation of urinary 8-OHdG with both smoking and drinking, but multiple regression analysis showed that smoking was not a significant factor. Age and gender were also non-significant factors. Conclusion: 8-OHdG, which is an indicator of oxidative DNA damage, was a sensitive biomarker for Cr exposure. |
| 關聯: | ULTRASOUND IN MEDICINE AND BIOLOGY 29(7):1027-1035 |
| 顯示於類別: | [台中附設醫院] 期刊論文
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