Breast cancer diagnosis using three-dimensional ultrasound and pixel relation analysis

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 台中附設醫院 > 期刊論文 > Item 310903500/29123

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题名:	Breast cancer diagnosis using three-dimensional ultrasound and pixel relation analysis
作者:	Chen, WM;Chang, RF;Moon, WK;Chen, DR
贡献者:	附設醫院外科部;China Med Coll & Hosp, Dept Gen Surg, Taichung, Taiwan;Natl Chung Cheng Univ, Dept Comp Sci & Informat Engn, Chiayi, Taiwan;Seoul Natl Univ Hosp, Dept Diagnost Radiol, Seoul 110744, South Korea
日期:	2003
上传时间:	2010-09-24 14:22:46 (UTC+8)
出版者:	ELSEVIER SCIENCE INC
摘要:	Aims: To investigate the concentration of urinary 8-hydroxydeoxyguanosine (8-OHdG) among electroplating workers in Taiwan. Methods: Fifty workers were selected from five chromium (Cr) electroplating plants in central Taiwan. The 20 control subjects were office workers with no previous exposure to Cr. Urinary 8-OHdG concentrations were determined using high performance liquid chromatography with electrochemical detection. Results: Urinary 8-OHdG concentrations among Cr workers (1149.5 pmol/kg/day) were higher than those in the control group (730.2 pmol/kg/day). There was a positive correlation between urinary 8-OHdG concentrations and urinary Cr concentration (r = 0.447, p < 0.01), and urinary 8-OHdG correlated positively with airborne Cr concentration (r = 0.285). Using multiple regression analysis, the factors that affected urinary 8-OHdG concentrations were alcohol, the common cold, and high urinary Cr concentration. There was a high correlation of urinary 8-OHdG with both smoking and drinking, but multiple regression analysis showed that smoking was not a significant factor. Age and gender were also non-significant factors. Conclusion: 8-OHdG, which is an indicator of oxidative DNA damage, was a sensitive biomarker for Cr exposure.
關聯:	ULTRASOUND IN MEDICINE AND BIOLOGY 29(7):1027-1035
显示于类别:	[台中附設醫院] 期刊論文

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