中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/7352
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    题名: Three New Flavonoids and Antiallergic, Anti-Inflammatory Constituents from the Heartwood of Dalbergia odorifera
    作者: 張永勳(Yuan Shiun Chang)
    贡献者: 藥學院中國藥學研究所;中國附醫藥劑部中藥局
    关键词: Dalbergia odorifera;Leguminosae;flavonoids;antiallergic activity;anti-inflammatory activity
    日期: 1998
    上传时间: 2009-08-26 16:21:02 (UTC+8)
    摘要: Three new flavonoids, (3R)-4′-methoxy-2′,3,7-trihydroxyisoflavanone (11), 7-methoxy-3,3′,4′,6-tetrahydroxyflavone (18), and 2′,7-dihydroxy-4′,5′-dimethoxyisoflavone (22), were isolated from the heartwood of Dalbergia odorifera T. Chen. (Leguminosae), together with twenty-two known compounds, (S)-4-methoxydalbergione (1), cearoin (2), medicarpin (3), formononetin (4), sativanone (5), 3-hydroxy-9-methoxy-coumestan (6), meliotocarpan A (7), isoliquiritigenin (8), stevein (9), liquiritigenin (10), 3′,4′,7-trihydroxyflavanone (12), butein (13), 3′-hydroxymelanettin (14), koparin (15), bowdichione (16), fisetin (17), melanettin (19), sulfuretin (20), 3′-hydroxydaidzein (21), 3′-O-methylviolanone (23), xenognosin B (24), and dalbergin (25). These flavonoids were evaluated in antiallergic and anti-inflammatory tests. The results showed that (S)-4-methoxydalbergione (1) and cearoin (2) exhibited antiallergic activity while (S)-4-methoxydalbergione (1), cearoin (2), butein (13), koparin (15), bowdichione (16), 3′-O-methylviolanone (23), and xenognosin B (24) showed significant anti-inflammatory activity.
    關聯: PLANTA MEDICA 64(2)153~158
    显示于类别:[中國藥學研究所(已停用)] 期刊論文

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