中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/6715
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    题名: Factors Associated with Peptic Ulcer in Taiwan:A case-control study
    其它题名: 消化性潰瘍的相關因子:病例對照研究
    作者: (Hwang-Huel Wang);(Huen-Wen Xiao);(Chien-Chang Liao);葉兆雲(Ip Siu-Wan)
    贡献者: 健康照護學院營養學系
    关键词: 病例對照研究;家族史;生活型態;消化性潰瘍;case-control study;family history;lifestyle;peptic ulcer
    日期: 2006.03
    上传时间: 2009-08-26 15:58:02 (UTC+8)
    摘要: 目的 本文比較消化性潰瘍病人與沒有消化性潰瘍病人的人口地理特徵、生活型態與消化性潰瘍的家族病史。方法 從2001到2002年期間,經由消化系醫師的診斷我們在一家醫學中心收集了消化性潰瘍的病例與對照。全部的參加者皆是醫院腸胃科18歲以上的門診病人且接受內視鏡的檢查。經由問卷訪視,我們收集了病例與對照的資料,包括年齡、身高、體重、血型、生活型態如抽菸及喝酒等、特定的飲食習慣如辛辣物及醋的攝食與家族病史等。結果 共有102位消化性潰瘍病例與71位對照,病例組的男性比例較對照組稍高。相對於對照組,病例組年紀較高及教育程度較低。由生活型態與飲食的資料顯示,病例組曾經有抽菸(44.1% vs 23.9%, P=0.02)、嚼檳榔(14.7% vs 2.8%, P=0.010)的比例都比對照組高。與大專教育程度的人相較,教育程度國中以下的人有較高的消化性潰瘍風險(OR=6.76, 95% CI=2.15-21.3)。自我陳述有壓力的人發生消化性潰瘍之危險比沒有壓力的人來得高(OR=4.96, 95%, CI=2.03-12.1)。結論 本研究結果顯示消化性潰瘍的發生可能與低教育程度、家族病史及自我陳述壓力相關,但需要更大型的臨床研究做進一步的探討。
    Purpose. This study compared demographic characteristics, lifestyle and family history of peptic ulcer disease (PUD) among patients with PUD and those without PUD. Methods. From 2001 to 2002, we recruited 102 patients with PUD among outpatients aged 18 years and older who had visited the gastrointestinal clinic and underwent endoscopy examinations at a medical center. Controls (N=71) comprised patients without PUD from the same clinic. We collected data on age, height, weight, blood type, lifestyle, such as smoking, areca quid chewing and alcohol drinking, specific dietary habits, such as spice and vinegar consumption, and family disease history by self-reported questionnaire interviews. Results. There was a higher proportion of males in the patient group compared with control group (65.7% vs 42.3%, p=0.002); individuals in the patient group were also older and had received lesser education than controls. Analyses on lifestyle and diet showed patients have higher ratio of smoking (44.1% vs 23.9%, p=0.02) and areca quid chewing (14.7% vs 2.8%, p=0.010) than controls. Compared with those who had more than 13 years of education, people educated 9-years and less were at a higher risk of peptic ulcer (OR=6.76, 95% CI=2.15 to 21.3). People with self-perceived stress were at higher risk of developing peptic ulcer than those who reported not having any stress (OR=4.96, 95% CI=2.03 to 12.1). Conclusions. Factors associated with PUD include low education, family history of the disease, and self-perceived stress. Larger scale studies are needed to further investigate the association.
    關聯: Mid-Taiwan Journal of Medicine 11(1 )1 ~8
    显示于类别:[營養學系暨碩士班 ] 期刊論文

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