中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/6555
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    题名: Impaired micturition reflex caused by acute selective dorsal or ventral root(s) rhizotomy in anesthetized rats
    作者: (Liao JM);(Cheng CL);李信達(Shin-Da Lee);(Chen GD);(Chen KJ);(Yang CH);(Pan SF);(Chen MJ);(Huang PC);(Lin TB)*
    贡献者: 健康照護學院物理治療學系
    关键词: cystometry;electromyogram;motor;sensory;spinal cord
    日期: 2006-04
    上传时间: 2009-08-26 15:54:38 (UTC+8)
    摘要: PURPOSE: To clarify the contributions of parasympathetic inputs and outputs to the micturition reflex. MATERIALS AND METHODS: Intra-vesical pressure (IVP), external urethral sphincter electromyogram (EMG), pelvic afferent nerve activities (PANA), and pelvic efferent nerve activities (PENA) as well as the time-derived IVP (dIVP, an index of bladder contractility) were evaluated in intact and acute dorsal or ventral root(s) rhizotomized (DRX and VRX, respectively) rats. RESULTS: In DRX rats, when compared with that in intact stage, the voiding frequency was decreased (75 +/- 15% of intact, P < 0.05, n = 8), while the threshold pressure to trigger voiding contractions was significantly increased (187 +/- 75% of intact, P < 0.05, n = 8). In addition, several insufficient contractions (5.3 +/- 3.5 contractions/voiding, P < 0.05, n = 8) occurred in ahead of each voiding contraction. On the other hand, in VRX rats, the peak and rebound IVP were significantly decreased (90 +/- 3.5% and 75 +/- 11.3% of intact, P < 0.01, n = 8), while the threshold pressure was not affected (102 +/- 11% of intact, P = NS, n = 8). The time-derived parameters were significantly decreased in VRX (peak dIVP, 78 +/- 10.2%, rebound dIVP, 75 +/- 15.6%, minimal dIVP, 68 +/- 14% of intact, P < 0.01, n = 8) but only peak dIVP was decreased (85 +/- 11% of intact, P < 0.01, n = 8) in DRX rats. CONCLUSION: Acute selective DRX and VRX rat can be an animal model to investigate peripheral neural control in micturition functions.
    關聯: NEUROUROLOGY AND URODYNAMICS 25(3 )283 ~289
    显示于类别:[物理治療學系(停用)] 期刊論文

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