The effects of one-week fluticasone propionate inhalation therapy for Tc-99m DTPA radioaerosol distribution in asthma of children: a preliminary report

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Title:	The effects of one-week fluticasone propionate inhalation therapy for Tc-99m DTPA radioaerosol distribution in asthma of children: a preliminary report
Authors:	(Chen AC);蔡輔仁(Fuu-Jen Tsai);(Tsai JJ);林正介(Cheng-Chieh Lin);李正淳(Cheng-Chun Lee);高嘉鴻(Chia-Hung Kao)
Contributors:	中醫學院學士後中醫學系學士班中醫基礎學科;中國附醫兒童醫學中心小兒遺傳科
Keywords:	Fluticasone propionate inhalation therapy;Tc-99m DTPA radioaerosol;Asthma
Date:	2003
Issue Date:	2009-08-26 15:21:38 (UTC+8)
Abstract:	This study evaluated the effects of fluticasone propionate inhalation therapy for the distribution pattern of Tc-99m DTPA radioaerosols in 10 children with asthma. The homogeneous degree of depositing Tc-99m DTPA radioaerosol was evaluated using a modified standard score system over the bilateral lungs. The baseline scores were calculated from Tc-99m DTPA radioaerosol inhalation lung scintigraphy before inhalation therapy (100 µg fluticasone propionate two times daily for one week), and the scores were recalculated after inhalation therapy to evaluate the effects of one-week of fluticasone propionate inhalation therapy for Tc-99m DTPA radioaerosol distribution patterns. After one week of fluticasone propionate inhalation therapy, the scores were decreased in all of the 10 children, which may mean that the bronchial constriction degree due to asthma is decreased. In addition, there was a significantly statistical difference in the scores before and after one-week fluticasone propionate inhalation therapy (p < 0.05). In conclusion, one-week fluticasone propionate inhalation therapy could significantly improve the bronchial constriction due to asthma in children based on the evidence of Tc-99m DTPA radioaerosol inhalation lung scintigraphic findings.
Relation:	LUNG 181(3)149 ~155
Appears in Collections:	[School of Post-Baccalaureate Chinese Medicine] Journal articles

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