Effects of Shao-Fu-Zhu-Yu-Tang on Motililty of Human Sperm.

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Title:	Effects of Shao-Fu-Zhu-Yu-Tang on Motililty of Human Sperm.
Authors:	(Ching-Chiang Yang)、(Jung-Chou Chen)、(Guang-Wei Chen)、(Yi-Shuan Chen)、鍾景光(Jing-Gung Chung)*
Contributors:	生命科學院生物科技學系;中國附醫醫學研究部 Shao-Fu-Zhu-Yu-Tang;sperm motility;acrosomal activity;free radicals;pre-medication;post-medication
Date:	2003
Issue Date:	2009-08-25 14:39:42 (UTC+8)
Abstract:	Shao-Fu-Zhu-Yu-Tang (SFZYT) is reportedly beneficial to sperm. In this study, we examined sperm acrosomal activity and serum free radical changes to evaluate the possible mechanism of SFZYT. A clinical study evaluated the sperm count and motility in 36 patients with chronic prostatitis before and after treatment for 60 days. The results revealed a significant increase in sperm motility after treatment as evaluated by computer-assisted semen analysis (17.27 ± 9.00 versus 28.29 ± 10.00, p < 0.01). An increase in sperm quantity and quality was observed by count and morphology with a high-powered intravital microscope. To gain an understanding of the mechanisms that caused this effect, we assessed sperm acrosin activity levels before (10.6 μ lu/106) and after medication (28.6 μ lu/106) (p < 0.01). The levels of the free radicals was relatively higher before medication, 2144, compared to a normal value of 780 after medication (p < 0.01). In conclusion, SFZYT increased the motility and quality of human semen and this increase is related to an increase in sperm acrosin activity. SFZYT also works as a sperm antioxidant and antiaging agent.
Relation:	The American Journal of Chinese Medicine 31(4 )573 ~579
Appears in Collections:	[Department of Biological Science and Technology] Journal articles

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