Serum dioxin levels in residents living in the vicinity of municipal waste incinerators in Taiwan

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Title:	Serum dioxin levels in residents living in the vicinity of municipal waste incinerators in Taiwan
Authors:	(Huang HY);(Jeng TY);(Lin YC);(Ma YC);(Kuo CP);宋鴻樟(Fung-Chang Sung)*
Contributors:	公共衛生學院環境醫學研究所
Keywords:	Inhalation Toxicology;Pulmonary Medicine
Date:	2007-05
Issue Date:	2009-08-25 14:30:23 (UTC+8)
Abstract:	This study used data obtained from the Taiwan Environmental Protection Administration to measure the dioxin exposure and the body burden for residents living in the vicinity of 19 municipal waste incinerators (MWIs). A survey was conducted in 1999-2003 for the residents. Approximately 16 ambient air samples and a 60-ml blood samples of 84 to 92 residents aged 18-65 yr were collected randomly in four zones (A, B, C, D) for each MWI site based on the atmospheric dispersion model (ADM). Zone A was defined with the highest pollution level, followed by zones B and C, and zone D (background level). Congeners of 17 polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) were determined for each sample. We summarized the PCDD/Fs levels in air samples and serum specimens by zone for these 19 sites. The mean ambient levels of PCDD/Fs fitted the ADM, the highest from zone A and the lowest from zone D (2.74 vs. 0.13 pg I-TEQ/Nm3). However, the mean serum concentration in zones A was not distinct from that in zones D (18.7 vs. 19.0 pg WHO-TEQ/g lipid). The age-specific average serum concentration increased from 13.27 pg WHO-TEQ/g in 18- to 25-yr-old subjects to 23.46 pg WHO-TEQ/g lipid in 56- to 65-yr-old subjects. In conclusion, the serum PCDD/Fs levels among residents did not adhere to the dispersion model for incineration emissions. The dose-response of serum PCDD/Fs by age suggests that the body burden of the chemicals is mainly associated with other sources instead of with inhalation.
Relation:	INHALATION TOXICOLOGY 19(5)399~403
Appears in Collections:	[Graduate Institute of Environmental Medicine] Journal articles

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