中國醫藥大學機構典藏 China Medical University Repository, Taiwan:Item 310903500/5950
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    Title: Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1-5 years in the Democratic Republic of Sao Tome and Principe, Western Africa.
    Authors: (Fan CK)*;(Hung CC);(Su KE);宋鴻樟(Fung-Chang Sung);(Chiou HY);(Gil V);(da Conceicao dos Reis Ferreira M);(de Carvalho JM);(Cruz C);(Lin YK);(Tseng LF);(Sao KY);(Chang WC);(Lan HS);(Chou SH)
    Contributors: 公共衛生學院環境醫學研究所
    Keywords: Toxoplasma gondii;Seroprevalence;Pre-schoolchildren;Latex agglutination test;Sao Tome and Principe
    Date: 2006-05
    Issue Date: 2009-08-25 14:30:00 (UTC+8)
    Abstract: The prevalence status of Toxoplasma gondii infection in children of the Democratic Republic of Sao Tome and Principe (DRSTP), Western Africa, is unknown to date. A serologic survey of T. gondii infection among pre-schoolchildren aged <5 years in the DRSTP was assessed by the latex agglutination (LA) test from November 2003 to March 2004. The overall seroprevalence of T. gondii infection was not low, reaching 21.49% (26/121). No significant gender difference in seroprevalence was found between boys (19.30%; 11/57) and girls (23.44%; 15/64) (χ2 = 0.31, P = 0.58). The older age group of 4–5 years had significantly higher seroprevalence (36.67%; 11/30) than the younger age group of <2 years (10.34%; 3/29) (χ2 = 5.64, P = 0.02). It was noteworthy that the majority of seropositive boys (90.91%; 10/11) or older children aged ≥2 years (82.61%; 19/23) had high LA titres of ≥1:1024, indirectly indicating acute Toxoplasma infection. This study is the first report indicating that T. gondii infection is not low in pre-schoolchildren aged <5 years in the DRSTP. Whether the DRSTP pre-schoolchildren acquire T. gondii infection through constant exposure to the parasite from their daily activities owing to poor environmental hygiene should be further evaluated.
    Relation: JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS 100(5)446~449
    Appears in Collections:[Graduate Institute of Environmental Medicine] Journal articles

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