Relative importance of atherosclerotic risk factors for coronary heart disease in Taiwan.

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Title:	Relative importance of atherosclerotic risk factors for coronary heart disease in Taiwan.
Authors:	(Chien KL);宋鴻樟(Fung-Chang Sung);(Hsu HC);(Su TC);(Chang WD);(Lee YT)
Contributors:	公共衛生學院環境醫學研究所
Keywords:	risk factors;coronary heart disease;cohort study
Date:	2005-04
Issue Date:	2009-08-25 14:29:35 (UTC+8)
Abstract:	Background: The relative importance of atherosclerotic risk factors, such as hypertension, dyslipidemia, diabetes and smoking, was associated with cardiovascular events and varied among different ethnic groups. For a population with relatively low coronary heart disease (CHD) such as Asian-Pacific countries, it is crucial to differentiate the roles of these risk factors. Methods: We examined the relative importance of various risk factors for CHD in a community-based cohort in Taiwan, consisting of 3602 adults aged 35 and older with a median follow-up time of 9.0 years since 1990. Regular death certificate verification and medical record reviews were performed in the follow-up activities. Results: There were 85 cases defined as CHD. In the Cox proportional hazard analysis, men were at higher risk than women [hazard risk (HR)=2.22, 95% confidence interval (CI)=1.39-3.56]. Hypertension was the most common risk factor for CHD. Dyslipidemia, especially lowered high-density lipoprotein cholesterol, also played an important role (HR=2.09, 95% CI=1.33-3.29) in CHD events. Hypertension had a greater influence in males (HR=6.08, P<0.001) than in females (HR=2.80, P<0.001). No independent association was found for smoking or body mass index in cardiovascular events. Conclusion: This study found that in a community-based cohort, hypertension, and dyslipidemia attribute an important role to cardiovascular events.
Relation:	EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION 12(2)95~101
Appears in Collections:	[Graduate Institute of Environmental Medicine] Journal articles

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