研究背景:
大腸直腸癌已經成為台灣發生率第一的癌症。有許多篩檢大腸直腸癌的工具可以使用,但目前仍有昂貴與風險性的考量。這個臨床試驗用良導絡檢測,比較罹患大腸直腸癌患者以及健康受試者的經絡穴位傳導值有何不同,期望透過良導絡測定對於經絡系統分析的研究,提供臟腑病變初期的預警參考,協助於中醫療程的掌握,為中醫診斷的客觀化提供依據。
研究方法:
利用橫斷性與相關性的研究設計,從2011年10月1日到2012年3月28日,招募於台中榮民總醫院大腸直腸科接受追蹤治療的受試者。利用良導絡經絡穴位儀來檢測受試者的經絡穴位傳導值,收集相關資料提供分析討論。
研究結果:
總共有35個大腸直腸癌受試者(平均年齡60.71±11.45)與22個健康受試者(平均年齡54.73±14.49)參與此研究。統計分析結果發現(1)經絡電位傳導總平均值在癌症組(20.78±13.47)低於正常組(30.64±19.2) (p=0.046);(2)心經、三焦經、膀胱經的平均值在癌症組(21.72±14.95,25.37±21.05,12.11±10.77)低於正常組(33.18±18.47,43.08±31.23,20.46±15.87)(p=0.015,p=0.044,p=0.020);(3)平均交感-副交感神經平衡指標癌症組(4.73±2.87)高於正常組(4.08±3.60)(p=0.041); (4)在癌症組中,CA-199異常(≧34)的患者其經絡電位傳導總平均值(5.77± 1.12)低於CA-199正常的患者(20.82±10.6)(p=0.036)。
結論:
本研究提供良導絡在大腸直腸癌病人臨床評估的參考資訊。
Purpose
Colorectal cancer ranked the first in the incidence of all the cancers in Taiwan. Multiple test options are available for screening, but some of them are expensive and risky. This study was designed to compare the meridian energy between subjects with and without colorectal cancers.
Materials and Methods
We applied a cross-sectional and correlational research design. The study included participants who had colorectal cancer or not at Veterans General Hospital in Taichung from 1st October 2010 to 31st March 2012. Meridian energy analysis device was used to exam the meridian electrical conductance of patients. All data were recorded and analyzed.
Results
There were 35 patients (aged 60.71 ± 11.45) who had colorectal cancer and 22 patients (age 54.73 ± 14.49) who had no colorectal cancer in the study. Statistical analysis showed that (1) the average of all the meridian energy in the cancer group (20.78±13.47) was decreased from that in normal group (30.64±19.2)(p =0.046); (2) the average of index of sympathetic- parasympathetic balance in the cancer group (4.73±2.87) was increased from that in normal group (4.08±3.60)(p=0.041); (3) the average of Heart Meridian, Triple Energizer Meridian, and Bladder Meridian in the cancer group (21.72±14.95, 25.37±21.05, 12.11±10.77) were decreased from that in the normal group) (33.18±18.47, 43.08±31.23, 20.46±15.87)(p=0.015, p=0.044, p=0.020) ;(4) in the cancer group, the average of all the meridian energy in the abnormal CA-199 group (5.77± 1.12) was decreased from that in the normal CA-199 group (20.82±10.6) (p=0.036).
Conclusions
This result provides some reference for evaluation of colorectal cancer patient using Meridian. Larger clinical trials are required to fully assess the benefits of Meridian for colorectal cancer.