利用電化學沈積法製造不銹鋼/聚乳酸複合人工骨支架之加工技術

CMUR > College of Medicine > Department of Biomedical Imaging and Radiological Science > Research reports > Item 310903500/44795

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Title:	利用電化學沈積法製造不銹鋼/聚乳酸複合人工骨支架之加工技術
Authors:	陳悅生(Yueh-Sheng Chen);樓靜文(Ching-Wen Lou)
Contributors:	健康照護學院生物醫學影像暨放射科學學系;中國附醫醫學研究部
Date:	2011-12-31
Issue Date:	2012-06-15 11:47:57 (UTC+8)
Abstract:	氫氧基磷灰石為一種具有骨引導性的材?，其一般成形方式為化學沉積法，通常生成磷灰石所需的時間為30天以上，如果?用電化學法?沉積氫氧基磷灰石，以將時間縮減成20分鐘，?但生產成本較低，而且節?生成氫氧基磷灰石時間。所形成的磷灰石與人體骨骼中的礦物質具有相似的鈣磷比，可以幫助成骨細胞於材?表面上的增生作用，加速骨骼恢?repair的速?。本研究的目的旨在設計製備多孔構造之?銹鋼/聚乳酸/氫氧基磷灰石複合編織物，實驗中擬將?銹鋼纖維/聚乳酸複絲經由16 錠的編帶機製造成?銹鋼/聚乳酸編織物，並改變捲取齒??及編帶齒?之比?，並觀察3D編織物composites的角?及孔隙面積porous area變化?挑選較佳之聚乳酸編織物。接續以電化學法沉積氫氧基磷灰石於3D聚乳酸編織物外層，並使用Scanning Electron Microscope (SEM)?觀察電化學法沉積氫氧基磷灰石之均勻?及以Energy Dispersive Spectrometer (EDS)檢測樣本上鈣磷成份的含有比?。 Hydroxyapatite is an osteoinductive material. It usually takes over thirty days to form the hydroxyapatite by chemical deposition, but it can be deducted to 20 minutes by electrochemical method which reduces the production cost and time largely. The hydroxyapatite has the similar Ca/P ratio to minerals existing in the human bones and could help osteoblast to proliferate on the scaffold and expedite the repair of the bones. The aim of this research is to manufacture the stainless steel/ polylactide/ hydroxyapatite composites with porous structure. This research proposes to fabricate the stainless steel/ polylactide composites by stainless steel/ polylactide ply yarns by 16-spindle braid machine, and the ratio of braid gear and take-up gear will be varied accordingly. The good 3D stainless steel/ polylactide composites will be chosen according to the angles and porous area, and then the hydroxyapatite will be deposited on its outer layer by electrochemical method. Finally, the stainless steel/ polylactide/ hydroxyapatite composites will be observed for the uniform dispersion of the hydroxyapatite using a scanning electron microscope (SEM), and the Ca/P ratio will be examined using an energy dispersive spectrometer (EDS).
Appears in Collections:	[Department of Biomedical Imaging and Radiological Science] Research reports

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