開發微生物及植物性產品取代含藥物飼料添加物

CMUR > College of Life Sciences > Department of Biological Science and Technology > Research reports > Item 310903500/44309

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Title:	開發微生物及植物性產品取代含藥物飼料添加物
Authors:	徐媛曼(Yuan-Man Hsu)
Contributors:	生命科學院生物科技學系
Keywords:	黃芩;梔子;沙門氏菌;複合益生菌;離乳仔豬;腸道健康;飼料添加物;免疫;球蟲;新城雞瘟疫苗;干擾素;免疫調控物;抗病毒;Scutellariae Radix;Gardeniae Fructus;Salmonella;multi-strain probiotic;weanling piglet;gut health;feed supplement;immunity;Eimenia spp.;Newcastle Disease Vaccine;interferon;immunomodulants;anti-virus
Date:	2011-12-31
Issue Date:	2012-06-13 10:53:32 (UTC+8)
Abstract:	畜牧生產過程中因預防、控制疾病或促進動物生長，而大量使用抗生素，導致病源菌之抗藥性增加及畜產品之藥物殘留問題，同時亦危及人體健康與環境污染。隨著各國對公共衛生之要求，已禁止多種抗生素添加於飼料中。為增強動物體抗病能力及降低疾病之損失，除了飼養環境之改善以降低對禽畜之緊迫外，多種保健性及抗病毒性產品藉由提升宿主之抵抗力，以降低病源感染傷害亦廣泛被重視。因此，本計畫之全程目標乃以改善禽畜腸道健康及免疫調節能力為研發目標，利用具有抑菌、提升免疫功能及改善動物體腸道健康之益生菌或植生物質，與具有抗病毒與抗病源菌能力之干擾素配合使用，開發多功能性之生技產品以取代含藥物之飼料添加物，建立無藥物或降低使用治療藥物之飼養環境，生產健康安全之畜產品。 For animal production, a great quantity of antibiotics was usually used for the prevention and control of the disease, and also for the growth promotion of animals. Such fact may lead to the problem of antibiotic resistance for some pathogenic bacteria and also the problem of residual drugs in animal products. Moreover, this may also cause a risk for public health and environment pollution. With the increasing concern for public health, the use of antibiotics as feed supplement has been gradually prohibited by many governments in the world. To enhance the health and growth performance for domestic animals, besides the improvement of the facility and conditions for animal husbandry, many health modulators and antivirus products aimed to prevent the host from infection by bacteria and virus and to promote the animal growth, have been developed. In this study, with an aim to improve the gut health and immunomodulating activities of domestic animals, including pigs and chickens, we shall develop and use of some probiotics, as well as herbal plant products, which are with antibacterial or immunomodulating potentials, for feed supplement use. Meanwhile, the antivirus and antibacterial activity of a recombinant interferon product from a biotech company in Taiwan will be evaluated for pig and chicken use. If possible, it well be used in combination with the probiotic and herbal products for animal supplement use. By this way, a multifunctional feed supplement product may be developed and used as a substitute of antibiotics. Using this multifunctional product, an animal growing environment without or with reduced use of drugs may be established and healthy as well as safe animal products can be produced.
Appears in Collections:	[Department of Biological Science and Technology] Research reports

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