Attributable mortality burden of metabolic syndrome: comparison with its individual components

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 公共衛生學院 > 醫務管理學系暨碩士班 > 期刊論文 > Item 310903500/43874

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题名:	Attributable mortality burden of metabolic syndrome: comparison with its individual components
作者:	溫啟邦(Chi Pang Wen);(Hui-Ting Chan);(Min-Kuang Tsai);(Ting-Yuan D Cheng);(Wen-Shen I Chung);(Yen-Chen Chang);(Hui-Ling Hsu);(Shan-Pou Tsai);(Chwen-Keng Tsao);(Jackson Jui Man Wai);許志成*
贡献者:	公共衛生學院醫務管理學系
关键词:	Metabolic syndrome;hypertension;diabetes
日期:	2011-08
上传时间:	2012-04-19 15:00:34 (UTC+8)
摘要:	Aim: To estimate the national prevalence, mortality risk and population mortality burden of metabolic syndrome, and compare the values with those of its individual components. Methods and results: A total of 486,341 apparently healthy adults who went through a screening programme in Taiwan were recruited from 1994 onwards. As of 2007, 15,268 deaths had occurred at least one year after the examination. Six definitions of metabolic syndrome were used. Components of metabolic syndrome include obesity, hypertension, hyperglycaemia, dyslipidaemia and albuminuria. Hazard ratios (HRs) were calculated using the Cox proportional hazard model. The population mortality burden considered both national prevalence and HRs. The national prevalence of metabolic syndrome defined by the Adult Treatment Panel (ATP) III was 16.3%, the HR for all causes was 1.36 (95%, CI 1.31–1.41) and the HR for cardiovascular disease (CVD) was 1.63 (95%, CI 1.51–1.77). The population mortality burden of metabolic syndrome was 5.5% for all causes, in contrast to 9.0% for hypertension, 8.9% for albuminuria, 6.6% for diabetes, 3.5% for dyslipidaemia and 1.5% for obesity. For CVD it was 9.4%, lower than 10.7% for albuminuria and 25.0% for hypertension. Conclusion: The mortality burden of metabolic syndrome was relatively small at national level. Three of the five components of metabolic syndrome alone, namely hypertension, diabetes and albuminuria, contributed more than metabolic syndrome to all-cause mortality. Successful management of any of these three components would have achieved a greater impact on mortality than management of metabolic syndrome.
關聯:	EUROPEAN JOURNAL OF CARDIOVASCULAR PREVENTION & REHABILITATION 18(4):561-573
显示于类别:	[醫務管理學系暨碩士班] 期刊論文

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