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題名:	èè¯èç²èåç©å°æéª¨ç´°èæ´»æ§å½±é¿åæ¢ Effects of Cistanche deserticola crude extract on the activity of osteoblast
作者:	é»å¿æ²»
貢獻者:	ä¸é«å¸ç³»ç¢©å£«ç application/pdf
關鍵詞:	ä¸è¥;èè¯è;æéª¨ç´°è;éª¨è³ªçé¬ç Chinese herbal medicine;Cistanche deserticola;osteoblast;osteoporosis
日期:	2011-07-01
上傳時間:	2011-10-17 16:06:40 (UTC+8)
出版者:	ä¸åé«è¥å¤§å¸
摘要:	éª¨è³ªçé¬çå¥½ç¼æ¼åç¶å¾çå©¦å¥³ï¼å¸¸é æèæ¤é«ã é«é¨èèé¨éª¨æã äººé¡çéª¨éª¼ç´æç¾åä¹åæçºçé²è¡éª¨éå¡ä½ç¨ï¼æ¤ä¸ä½ç¨åæ¬éª¨é ç çæèæº¶èå©ç¨®ä½ç¨ï¼éª¨è³ªçé¬çå³æ¯æ¤å©ç¨®ä½ç¨å¤±å»å¹³è¡¡æé æãè å¶ä¸çæä½ç¨ç±æéª¨ç´°èæä¸»å°ï¼æ¬ç ç©¶å°æ¢è¨ä¸è¥å°æ¼æéª¨ç´°èæ´»æ§ çå½±é¿ã æ¬ç ç©¶é¸å®åäºç¨®å¸¸è¦è£èå¼·çéª¨ä¸è¥ç²èåç©ï¼ä¸¦ä»¥ MC3T3-E1 æéª¨ç´°èæ ªä¾æ¢è¨ãå¯¦é©åæå©é¨åï¼ç¬¬ä¸é¨ä»½è©ä¼°åäºç¨®ä¸è¥ç²èå ç©å° MC3T3-E1 æéª¨ç´°èæ ªçå½±é¿ãç¬¬äºé¨åé¸å®å¶ä¸ææè¥ç©èè¯è ä¸¦å°å¶æ©è½åé²ä¸æ¥çæ¢è¨ã çµæé¡¯ç¤ºï¼èè¯èè½å¤ ä¿é² MC3T3-E1æéª¨ç´°èæ ªçæ´»æ§èå å¼·ç¤¦ åä½ç¨ï¼æ ¹ææ¬ç ç©¶ççµæï¼èè¯èç²èåç©å¯çºéª¨è³ªçé¬ççæ²»çæ ä¾ä¸åæ°çæ¹åã Osteoporosis frequently occurs in women after menopause, often caused fracture of vertebral body, hip and wrist. About ten percent of human bone role in the effect of bone remodeling includes both bone formation and dissolution. Osteoporosis took place by the unbalance of these two effects. Osteoblasts make bone formation and in this study we explore Chinese herbal medicine for the activity of osteoblast. Our study used twelve selected common Bushen chinese herbal medicine crude extracts and MC3T3-E1 osteoblast cell line. Our research divided into two parts. The first part was to evaluate the effect of the twelve Bushen chinese herbal medicine crude extracts on MC3T3-E1 osteoblast cell line. Then we selected one of the effective drugs C. deserticola to make more advanced study. Our results revealed C. deserticola promote cell activity and mineralization in MC3T3-E1 osteoblast cell line. According to the results of this study, C. deserticola extracts provide a new direction for the treatment of osteoporosis.
顯示於類別:	[中醫學系暨碩博班] 博碩士論文

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