| 摘要: | 取假繁縷全草以甲醇重複浸泡三次，將粗萃物利用管柱層析法以梯度沖提法等分離技術做分離純化。
經分離純化後共得四十個化合物，其中包括
十六個單苯環類：
Benzoic acid (AR1) , 4-Hydroxybenzoic acid (AR2) , 4-Hydroxybenz -aldehyde (AR3) , 4-Hydroxyacetophenone (AR4) , Methyl 4-Hydroxybenzoate (AR5) , p-Anisic acid (AR6) , Vanillin (AR7) , 4-Hydroxy-3-methoxyacetophenone (AR8), Acetosyringone (AR9) , 4-Hydroxy-3, 5-dimethoxybenzaldehyde (AR10) , 4-Hydroxybenzyl alcohol ( AR11 ) , 2-(4-Hydroxyphenyl)ethanol (AR12) , Cinnamic acid (AR13) , 3-(4'-Hydroxyphenyl)-(E)-propenoic acid methyl ester (AR14) , (E)-Methyl 3-(4-hydroxy-3-methoxyphenyl)acrylate (AR15) , trans-Ferulic acid (AR16)
十個黃酮類：
5, 7, 4’-Trihydroxyflavonol (FL1) , 6, 8-Dimethyl-5, 7, 4’-trihydroxyflavone (FL2) , 5, 7-Dihydroxy-6, 8-dimethylflavone (FL3) , 5,4’-Dihydroxy-7-methoxy-6, 8-dimethylflavone (FL4) , 7-Hydroxy-5-methoxy-6, 8-dimethylflavanone (FL5) , 3-Hydroxy-5, 7-dimethoxy-6, 8-dimethylflavone (FL6*) , 7-Hydroxy-5-methoxy-6, 8-dimethylflavone (FL7*) , 7-Hydroxy-5-methoxy-6-methylflavanone (FL8*) , 5-Hydroxy-8-hydroxymethyl-7-methoxy-6-methylflavone (FL9*) , 5,7-Dihydroxy-4’-methoxy-6,8-dimethylflavone (FL10**)
一個葉綠素：
132(R)-Pheophytin a (CH1)
三個固醇類：
β-Sitosterol (ST1) , Stigmasterol (ST2) , Spinasterol (ST3)
四個三萜類：
Spergulagenin A (TR1 ) , Spergulagenin B (TR2 ) , Spergulagenin C (TR3 ) , Spergulagenin D (TR4 )
六個其它：
(OT1) , Loliolide (OT2) , 4, 4’-Dihydroxy-3, 3’-dimethoxybenzophenone (OT3) , (S)-Dehydrovomifoliol (OT4) , N-trans-Feruloyltyramine (OT5) , 2,3-Dihydroxypropyl hexadecanoate (OT6)
*新化合物
**由天然物首次分離
The whole herb of Glinus oppositifolius was extracted with methanol for three times. Take the extract used chromatography on silica gel with a gradient solvent system.
Fourty compounds have been isolated and purified. Those include sixteen aromatics: Benzoic acid (AR1) , 4-Hydroxybenzoic acid (AR2) , 4-Hydroxybenz -aldehyde (AR3) , 4-Hydroxyacetophenone (AR4) , Methyl 4-Hydroxybenzoate (AR5) , p-Anisic acid (AR6) , Vanillin (AR7) , 4-Hydroxy-3-methoxyacetophenone (AR8), Acetosyringone (AR9) , 4-Hydroxy-3, 5-dimethoxybenzaldehyde (AR10) , 4-Hydroxybenzyl alcohol ( AR11 ) , 2-(4-Hydroxyphenyl)ethanol (AR12) , Cinnamic acid (AR13) , 3-(4'-Hydroxyphenyl)-(E)-propenoic acid methyl ester (AR14) , (E)-Methyl 3-(4-hydroxy-3-methoxyphenyl)acrylate (AR15) , trans-Ferulic acid (AR16) ; ten flavonoids : 5, 7, 4’-Trihydroxyflavonol (FL1) , 6, 8-Dimethyl-5, 7, 4’-trihydroxyflavone (FL2) , 5, 7-Dihydroxy-6, 8-dimethylflavone (FL3) , 5,4’-Dihydroxy-7-methoxy-6, 8-dimethylflavone (FL4) , 7-Hydroxy-5-methoxy-6, 8-dimethylflavanone (FL5) , 3-Hydroxy-5, 7-dimethoxy-6, 8-dimethylflavone (FL6*) , 7-Hydroxy-5-methoxy-6, 8-dimethylflavone (FL7*) , 7-Hydroxy-5-methoxy-6-methylflavanone (FL8*) , 5-Hydroxy-8-hydroxymethyl-7-methoxy-6-methylflavone (FL9*) , 5,7-Dihydroxy-4’-methoxy-6,8-dimethylflavone (FL10**) ; one chlorophyll : 132(R)-Pheophytin a (CH1) ; three steroids : β-Sitosterol (ST1) , Stigmasterol (ST2) , Spinasterol (ST3) ; fours triterpenoids : Spergulagenin A (TR1 ) , Spergulagenin B (TR2 ) , Spergulagenin C (TR3 ) , Spergulagenin D (TR4 ) ; six oters: Lyciumamid (OT1) , Loliolide (OT2) , 4, 4’-Dihydroxy-3, 3’-dimethoxybenzophenone (OT3) , (S)-Dehydrovomifoliol (OT4) , N-trans-Feruloyltyramine (OT5) , 2,3-Dihydroxypropyl hexadecanoate (OT6)
* New compound
** First isolation from natural source |
