遠紅外線刺激在癲癇患者腦波變化之研究

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题名:	遠紅外線刺激在癲癇患者腦波變化之研究 The study of electroencephalography in epilepsy patients after far infrared ray stimulation
作者:	劉彥良
贡献者:	中西醫結合研究所碩士班
关键词:	遠紅外線刺激;癲癇;腦電波圖 Far infrared ray;epilepsy;acupuncture;large intestine acupuncture points 14
日期:	2011-07-15
上传时间:	2011-10-17 15:45:00 (UTC+8)
出版者:	中國醫藥大學
摘要:	目的：研究遠紅外線穴位刺激在癲癇患者的腦波變化，同時評估患者在接受刺激後癲癇發作次數的狀況。材料與方法：15位符合收案條件的癲癇患者，接受第一次腦波檢測後，先貼附28天對照組貼片於兩臂外側三角肌止點(臂臑穴)，貼附的方法採兩天貼一次，每次貼附20小時以上。28天後接受第二次腦波檢測並評估癲癇發作情形。休息14天後，接受第三次腦波檢測，接著以相同貼覆方式貼附28天試驗組貼片，之後接受第四次腦波檢測並評估癲癇發作情形。成果：15位癲癇患者各頻率的腦波變化並無顯著差異。但其中有一位頂葉腫瘤患者貼附試驗組貼片後發作情形顯著改善，同時腦部放電波在第四次腦波檢測中消失。結論：低功率遠紅外線刺激似難引起癲癇患者特定頻率腦波一致性的改變，但似乎對某些患者有所療效。 Objectives: To investigate the changes of electroencephalography (EEG) in epileptic patients and the efficacy of far infrared ray stimulation compared with placebo. Methods: A total of 15 patients with epilepsy were enrolled in the study. Those who received anti-epileptic drug(s) for more than one year and fulfill the criteria of seizure free was excluded. Patient would receive the first time EEG and then the placebo patches would be placed in the position of bilateral large intestine 14 (LI14) acupuncture points every other day for 28 days. And then patient received the second time EEG and the evaluation of efficacy. After that, patient would take a rest for 14 days for the purpose of decreasing the possible placebo effect. And then patient would receive the third time EEG. After that, the far infrared ray patches were placed in the same acupuncture points every other day for another 28 days. And then patient received the fourth time EEG and the evaluation of efficacy. The evaluations of efficacy were done by the clinician who was blind to our study. The EEG frequency Frequency domain analysis of EEG results were done by using the software of BrainVision Analyzer 2.0.1. And the mean activity was computed separately for the frequency bands: δ(0.5-3Hz)，θ(4-7Hz)、α(8-12Hz)、and β(13-30Hz). Result: There was no statistical significance of δ, θ, α, and β activity But one patient reported that after receiving far infrared ray stimulation, there was sleep benefit and the seizure frequency decreasing. Also in this patient, there were epileptic form discharge at the first, second, and third but not the fourth EEG. Conclusion: Far-infrared ray stimulation did not cause change of electroencephalography in our study. But in patient with some kind of epilepsy, such as brain tumor related seizure disorder or parietal lobe seizure, it may do some benefit. Further study of this issue may offer us answers in the near feature.
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