Detection of recurrent nasopharyngeal carcinomas with positron emission tomography using 18-fluoro-2-deoxyglucose in patients with indeterminate magnetic resonance imaging findings after radiotherapy

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Title:	Detection of recurrent nasopharyngeal carcinomas with positron emission tomography using 18-fluoro-2-deoxyglucose in patients with indeterminate magnetic resonance imaging findings after radiotherapy
Authors:	蔡銘修(Tsai,Ming-Hsui);(Shiau YC);高嘉鴻(Chia-Hung Kao)*;孫盛生(Shung-Shung Sun);林正介(Cheng-Chieh Lin);李正淳(Cheng-Chun Lee)
Contributors:	醫學院醫學系學士班耳鼻喉學科;中國附醫耳鼻喉部
Date:	2002-05
Issue Date:	2009-08-20 18:48:15 (UTC+8)
Abstract:	PURPOSE: The aim of this study was to evaluate the effectiveness of positron emission tomography (PET) using 18-fluoro-2-deoxyglucose (FDG) to detect recurrent nasopharyngeal carcinomas (NPC) when magnetic resonance imaging (MRI) findings are indeterminate. PATIENTS AND METHODS: After radiotherapy, 28 NPC patients with indeterminate MRI findings were included. MRI, FDG-PET, and biopsy were performed at least 4 months after radiotherapy and within 1 week. The final results were based on histopathologic findings and a clinical follow-up of at least 6 months. RESULTS: For detecting recurrent NPC in indeterminate MRI findings, the sensitivity, specificity and accuracy of FDG-PET were 100.0%, 92.9% and 96.4%, respectively. CONCLUSIONS: Based on these results, we can recommend FDG-PET for detecting recurrent NPC when MRI findings are indeterminate.
Relation:	JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 128(5):279~282
Appears in Collections:	[School of Medicine] Journal articles

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