結核病罹病因素的個案對照研究

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 公共衛生學院 > 環境醫學研究所(已停用) > 博碩士論文 > Item 310903500/32415

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題名:	結核病罹病因素的個案對照研究 Risk Factors of Tuberculosis Infection: A Case-Control Study
作者:	杜依璇;Yi-Hsuan Tu
貢獻者:	公共衛生學院環境醫學研究所碩士班
關鍵詞:	結核病;健康行為;共病關係;tuberculosis;health behavior;co-morbidity
日期:	2010
上傳時間:	2010-09-29 12:03:21 (UTC+8)
摘要:	目的：本研究主要探討結核病個案的健康行為、共病情形及環境暴露因素，和結核病疾病的相關性。方法：本研究採用結構式問卷的設計，透過行政院衛生署疾病管制局取得個案名冊，並經受訓後的訪員進行問卷的發放及收集，個案的名冊選擇採用隨機方式，與家屬及一般民眾做對照研究，資料完整可供分析之資料合計有病例590份，家屬對照399份和社區居民對照1149份。結果：本研究以羅吉斯迴歸（logistic regression）分析2,138位接受訪視者，發現具有以下特性之結核病罹病者顯著較優勢的變項，分別為：男性、年長者、家中所有成員一個月的平均收入較低者、父母親其中一方或兩方是原住民者(OR = 2.24, 95% CI : 1.20-4.18)、單身者(OR = 3.03, 95% CI : 1.80-5.09)、離婚或喪偶者(OR = 2.38, 95% CI : 1.46-3.89)、失業超過3個月或以上(OR = 1.45, 95% CI : 1.04-2.03)、同辦公室的人被診斷為肺結核者(OR = 9.17, 95% CI : 3.11-27.00)、被診斷出有糖尿病需要治療者(OR = 4.55, 95% CI : 3.11-6.66)。結論：本研究結果中發現，結核病的顯著相關罹病因素，包括種族、單身者、離婚或喪偶者、社會經濟因素（家戶收入），及診斷共病因素（糖尿病患者）。結核病防治應重視弱勢人口。 Purpose：This study examined relationships between tuberculosis (Tb) and the patient health behavior, co-morbidity conditions and environmental exposure factors. Methods：A questionnaire survey was conducted among patients with TB and two control groups consisted of a group of family members and another group of neighbors. Patients with TB were randomly selected from patients registered at the Centers for Disease Control. Interviewers completed interviews in person with eligible data of 590 patients with TB, 399 family members and 1149 community controls. Results：The multivariate logistic regression analysis showed that factors associated with the increased risk of tuberculosis included males, older age, low social economic status, indigenous parent(s) (OR = 2.24, 95% CI : 1.20-4.18), single(OR = 3.03, 95% CI : 1.80-5.09), divorced or widowed (OR = 2.38, 95% CI : 1.46-3.89), unemployed for over 3 months (OR = 1.45, 95% CI : 1.04-2.03), colleague with tuberculosis (OR = 9.17, 95% CI : 3.11-27.00) and with comorbidity of diabetes mellitus(OR = 4.55, 95% CI : 3.11-6.66)。 Conclusions：This study revealed race, single, divorced or losing one's spouse, low social economic status and diabetes are at high risk for the tuberculosis. The results reflect that the disadvantaged population deserve greater attention in the prevention and treatment of the disease.
顯示於類別:	[環境醫學研究所(已停用)] 博碩士論文

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