| 摘要: | Objectives: The aim of this study was to investigate the effects of the menstrual cycle on the pulse pressure waveforms in women with regular biphasic cycles.
Methods: We recruited 36 biphasic healthy eumenorrheic volunteers. Pulse pressure waveforms from the radial artery were recorded by sphygmography in both hands, each with three measurement positions and three different preload pressures, in a total of 18 measured points. The experimental design was single blinded and the technician who measured the waveforms did not know the menstrual time point of the subjects. The parameters included the pulse rate (PR), the height of the main wave (h1), the height of the dicrotic wave (h3), the rapid ejection time, the single systolic area (sSA), and the 1-minute systolic area (tSA).
Results: Our results showed that PR was significantly greater during the luteal phase (81.5±1.5/minutes versus 78.3±1.5/minutes, p<0.05) with an accompanying greater h1, h3, sSA, and tSA (p<0.05). We also demonstrated that h1, h3, sSA, and tSA increased with preload pressures and decreased when the detector was moved proximally, possibly a resultant of differences in the diameter and depth of radial artery. Furthermore, we found that h3 taken from the right hand was larger than that taken from the left hand and may reflect a shorter and simpler route of the right radial artery.
Conclusions: We conclude that pulse waveforms taken from the radial artery may assist in the identification of greater plasma volume, ventricular ejection volume, and vasodilatation increase in the luteal compared to the follicular phase. |
