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| 題名: | Effects of glucose fructose and 5-hydroxymethyl-2-furaldehyde on the presystemic metabolism and absorption of glycyrrhizin in rabbits |
| 作者: | Hou, YC;Ching, H;Chao, PDL;Tsai, SY;Wen, KC;Hsieh, PH;Hsiu, SL |
| 貢獻者: | 藥學院藥學系;China Med Univ, Sch Pharm, Taichung 404, Taiwan;China Med Univ, Sch Chinese Med, Taichung 404, Taiwan;China Med Univ, Inst Chinese Pharmaceut Sci, Taichung 404, Taiwan;China Med Univ, Sch Cosmeceut, Taichung 404, Taiwan |
| 日期: | 2005 |
| 上傳時間: | 2010-09-24 18:56:14 (UTC+8) |
| 出版者: | ROYAL PHARMACEUTICAL SOC GREAT BRITAIN |
| 摘要: | Serum albumin (sALB) is routinely determined in blood tests and is an excellent predictor of risk for many medical illnesses. Hypoalbuminemia has been sporadically reported in patients with psychiatric disorders, such as major depressive disorder and schizophrenia. We compared sALB levels between 19 drug-free patients of major depressive disorder with a control group of matching diets. We conducted this study by controlling the nutrition factor by assessing patient's diets, as well as other possible confounding factors such as sex, age, body mass index (BMI), liver function, and exercise, while focusing on hypoalbuminemia in patients with major depressive disorder. There is no difference in age, gender distribution, and dietary frequency on protein and albumin intake between the patient and control group. The sALB levels of the group with major depressive disorder were significantly reduced (p=0.049). The severity of depression is negatively correlated to the sALB level (r=-0.46, p=0.04). Hypoalbuminemia has clinical meanings on severity of depression and is independent of malnutrition. However, our results can only be seen as very preliminary and should be confirmed by larger studies. (C) 2004 Elsevier B.V. and ECNP. All rights reserved. |
| 關聯: | JOURNAL OF PHARMACY AND PHARMACOLOGY 57(2):247-251 |
| 顯示於類別: | [藥學系暨碩博士班] 期刊論文
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