Degradation of flavonoid aglycones by rabbit, rat and human fecal flora

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Title:	Degradation of flavonoid aglycones by rabbit, rat and human fecal flora
Authors:	Lin, YT;Hsiu, SL;Hou, YC;Chen, HY;Chao, PDL
Contributors:	藥學院藥學系;China Med Coll, Dept Pharm, Taichung, Taiwan;China Med Coll, Grad Inst Pharmaceut Chem, Taichung, Taiwan;Dept Hlth, Natl Labs Foods & Drugs, Taipei, Taiwan;China Med Coll, Sch Chinese Med, Taichung, Taiwan
Date:	2003
Issue Date:	2010-09-24 18:55:54 (UTC+8)
Publisher:	PHARMACEUTICAL SOC JAPAN
Abstract:	This study evaluated a continuous home-visiting program designed for disabled patients. An intervention program was also designed for caregivers that included education and disabled care skills training, and emotional support over a 22-week period. The criteria for the disabled patients were as follows: (1) aged 18 years or older, (2) Barthel activity of daily living (ADL) score of < 80 on the first visit, and (3) onset of disability prior to study was less than 2 years. A total of 126 participants were transferred from several hospitals to the community to be cared for by caregivers. Patients were divided into two groups: control group (n = 56), and intervention group (n = 70). In the control group, caregivers were not provided with any special training and patients were just evaluated at the beginning and end of the program. In the intervention group, caregivers were given intensive training in care for the disabled and completed eight home-visits. The outcomes were measured before and after program using Barthel ADL index, life satisfaction scale (LSS) and caregiver's burnout scale (CBS). The results showed that improvements in ADL, LSS and CBS were significantly greater in the intervention group, compared to the control group. Multiple linear regression models showed that improvements in ADL were higher among patients with early-stage (onset of disability was less than 6 months before the start of the program) disability, patients whose caregivers had good health status, patients in the intervention group and patients who received more daily care hours. For LSS, there was a negative correlation with change in CBS and financial burden. In conclusion, the intervention program significantly improved disabled patients' ADL scores, as well as caregivers' LSS and CBS scores. It is necessary to coordinate medical and public health resources in the community to provide disabled patients and their caregivers with specific training and caregiving skills. (C) 2002 Published by Elsevier Science Ireland Ltd.
Relation:	BIOLOGICAL & PHARMACEUTICAL BULLETIN 26(5):747-751
Appears in Collections:	[School of Pharmacy/Master Degree Program, Ph. D program] Journal articles

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