資料載入中.....
|
請使用永久網址來引用或連結此文件:
http://ir.cmu.edu.tw/ir/handle/310903500/30898
|
| 題名: | 6-PENTADECYLSALICYLIC ACID - AN ANTITHROMBIN COMPONENT ISOLATED FROM THE STEM OF RHUS-SEMIALATA VAR ROXBURGHII |
| 作者: | KUO, SC;TENG, CM;LEE, LG;CHIU, TH;WU, TS;HUANG, SC;WU, JB;SHIEH, TY;CHANG, RJ;CHOU, TC |
| 貢獻者: | 藥學院藥化所;KUO, SC, CHINA MED COLL,GRAD INST PHARMACEUT CHEM,91 HSUEH SHIH RD,TAICHUNG,TAIWAN |
| 日期: | 1991 |
| 上傳時間: | 2010-09-24 15:05:38 (UTC+8) |
| 出版者: | GEORG THIEME VERLAG |
| 摘要: | Chieh-pu-warn (CPW), or Swift-footed pill, is a traditional Chinese herbal preparation for the treatment of weakness, paralysis, or arthritis. Toxicity studies in mice showed that CPW at the maximal tested dosage (25 g/kg, p.o.) exhibited no acute toxicity. Subacute treatment of CPW with recommended daily dose (2.5 g/kg, p.o. daily for 15 days) showed that the body weight and the water content of lung, heart, kidney, and liver in mice were not changed significantly. The antiinflammatory effect of CPW was evaluated with carrageenin- and Freund's complete adjuvant-induced edematous responses in the hind paws of rats. It was found that a single dose (2.5 g/kg, p.o.) of CPW had no significant antiinflammatory effect, but consecutive pretreatment with the same dose for three days significantly inhibited the carrageenin-induced acute inflammation and Freund's complete adjuvant-induced subacute inflammation in rats. The present results suggest that CPW has antiinflammatory activities with low toxicities. |
| 關聯: | PLANTA MEDICA 57(3):247-249 |
| 顯示於類別: | [藥物化學研究所] 期刊論文
|
在CMUR中所有的資料項目都受到原著作權保護.
|
