Effect of CDA-II, urinary preparation, on lipofuscin, lipid peroxidation and antioxidant systems in young and middle-aged rat brain

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Title:	Effect of CDA-II, urinary preparation, on lipofuscin, lipid peroxidation and antioxidant systems in young and middle-aged rat brain
Authors:	Lin, WC;Wu, YW;Lai, TY;Liau, MC
Contributors:	醫學院醫學系藥理學科;China Med Coll, Dept Pharmacol, Taichung, Taiwan
Date:	2001
Issue Date:	2010-09-24 15:04:09 (UTC+8)
Publisher:	INST ADVANCED RESEARCH ASIAN SCIENCE & MEDICINE, INC
Abstract:	The purpose of the study was to investigate the effects of two constituents of Panax notoginseng flower extract, Ginsenoside Rb2 and Rc, on human sperm motility and progression in vitro. Semen samples were collected from 20 patients with sperm motility between 20% and 40% of normal. All samples had sperm counts of over 20 million per milliliter, in accordance with the World Health Organization standard. Sperm were separated by a Pet-cell discontinuous gr adient technique, and divided into a Percoll sperm control group, and three Ginsenoside Rb2 experimental groups (0.1, 0.01 and 0.001 mg/ml) and three Ginsenoside Rc experimental groups (0.1,0.01 and 0.001 mg/ml). The results showed that at concentrations of 0.01 mg/ml and 0.001 mg/ml, Ginsenoside Rc enhanced both sperm motility and sperm progression significantly at the end of the 1st and 2nd hour. However, the three concentrations of Ginsenoside Rb2 did not increase sperm motility at the 1st or 2nd hour, but promoted sperm progression at the 2nd hour, when compared to the Percoll group.
Relation:	AMERICAN JOURNAL OF CHINESE MEDICINE 29(1):91-99
Appears in Collections:	[School of Medicine] Journal articles

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