Novel distribution of calcitonin gene-related peptide in rodent subcommissural organs

中國醫藥大學機構典藏 China Medical University Repository, Taiwan > 醫學院 > 醫學系 > 期刊論文 > Item 310903500/30850

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题名:	Novel distribution of calcitonin gene-related peptide in rodent subcommissural organs
作者:	Tsai, MH;Wu, CH;Chen, WP;Shieh, JY;Wen, CY
贡献者:	醫學院醫學系解剖學科;Natl Taiwan Univ, Coll Med, Dept Anat & Cell Biol, Taipei 10018, Taiwan;China Med Coll, Dept Anat, Taichung 404, Taiwan;Natl Def Med Ctr, Dept Biol & Anat, Taipei 114, Taiwan
日期:	2003
上传时间:	2010-09-24 15:03:21 (UTC+8)
出版者:	LIPPINCOTT WILLIAMS & WILKINS
摘要:	Our aim was to compare Taxol-based chemotherapy response of non-small cell lung cancer (NSCLC) with P-glycoprotein (Pgp) or lung resistance protein expression (LRP). Immunohistochemical analyses were performed on multiple nonconsecutive sections of the biopsy specimens to detect Pgp and LPR expressions in 40 patients with advanced NSCLC before Taxol-based chemotherapy. The chemotherapy response was evaluated by clinical and radiological methods in the third month after completion of treatment. No significant differences of prognostic factors (age, sex, body weight loss, performance status, tumor size, tumor stage, and tumor cell type) were found between the 20 patients with good and the 20 patients with poor responses. The incidence difference of positive Pgp expressions between good and poor responses was significant, however, the difference of LRP expression was not. We concluded that Taxol-based chemotherapy response of patients with NSCLC was related to Pgp but not LPR expression.
關聯:	NEUROREPORT 14(14):1851-1856
显示于类别:	[醫學系] 期刊論文

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