In vitro propagation by asymbiotic seed germination and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity studies of tissue culture raised plants of three medicinally important species of Dendrobium

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Title:	In vitro propagation by asymbiotic seed germination and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity studies of tissue culture raised plants of three medicinally important species of Dendrobium
Authors:	Lo, SF;Nalawade, SM;Mulabagal, V;Matthew, S;Chen, CL;Kuo, CL;Tsay, HS
Contributors:	藥學院中藥所;Chaoyang Univ Technol, Inst Biotechnol, Taichung 413, Taiwan;Inst Agr Res, Chiayi Agr Expt Stn, Dept Agron, Chiayi 600, Taiwan;Natl Chung Hsing Univ, Dept Agron, Taichung 402, Taiwan;Chaoyang Univ Technol, Inst Biotechnol, Taichung 413, Taiwan;China Med Univ, Inst Chinese Pharmaceut Sci, Taichung 404, Taiwan
Date:	2004
Issue Date:	2010-09-24 15:02:28 (UTC+8)
Publisher:	PHARMACEUTICAL SOC JAPAN
Abstract:	The purpose of this study was to examine whether mechanical tensile forces affect estrogen regulation of collagen synthesis of anterior cruciate ligament fibroblasts at the mRNA level. Estrogen was studied at three physiologic levels, 10(-11), 10(-10), and 10(-9) M. The results revealed that estrogen alone stimulated Type I and III collagen synthesis at the mRNA level, and application of mechanical force decreased the expression of collagen Type I and III genes at all tested estrogen levels. These findings suggest that estrogen may directly regulate ligament structure and function by alteration of Type I and III collagen synthesis. This regulation is dependent on mechanical loading. (C) 2004 Elsevier Inc. All rights reserved.
Relation:	BIOLOGICAL & PHARMACEUTICAL BULLETIN 27(5):731-735
Appears in Collections:	[Graduate Institute of Chinese Pharmaceutical Science] Journal articles

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