Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features

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Title:	Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features
Authors:	Lin, SY;Yeh, KT;Chen, WTL;Chen, HC;Chen, ST;Chiou, HY;Chang, JG
Contributors:	附設醫院醫研部分子醫學中心;China Med Univ, Dept Mol Med, Taichung, Taiwan;Chang Hua Christian Hosp, Div Proctol, Dept Surg, Changhua, Peoples R China;Chang Hua Christian Hosp, Dept Pathol, Changhua, Peoples R China;Taipei Med Univ, Dept Publ Hlth, Taipei, Taiwan;Taipei Med Univ, Dept Internal Med, Taipei, Taiwan;Taipei Med Univ Hosp, Dept Internal Med, Taipei, Taiwan
Date:	2004
Issue Date:	2010-09-24 15:01:33 (UTC+8)
Publisher:	PROFESSOR D A SPANDIDOS
Abstract:	The aim of this study is to prepare networks of Bloom number 300 gelatin and genipin as degradable biomaterials. The cross-linking ability of genipin on gelatin was studied and discs were made from the genipin-fixed gelatin. The swelling ratio, the degree of cross-linking, and the rate of degradation of the discs were measured using ninhydrin assay and differential scanning calorimetry (DSC) experiments. The results indicated that genipin is a good cross-linker for the gelatin. Additionally, varying the concentration of genipin can control the rate of degradation and the degree of cross-linking of the genipin-fixed gelatin. Finally, the concentration of genipin should exceed 0.5% of the overall weight of the gelatin-based material if a complete cross-linking reaction between gelatin and genipin molecules is required. (C) 2003 Elsevier B.V. All rights reserved.
Relation:	ONCOLOGY REPORTS 11(2):341-348
Appears in Collections:	[China Medical University Hospital] Jurnal articles

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