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請使用永久網址來引用或連結此文件:
http://ir.cmu.edu.tw/ir/handle/310903500/30766
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| 題名: | Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock |
| 作者: | Fang, SH;Hou, YC;Chang, WC;Hsiu, SL;Chao, PDL;Chiang, BL |
| 貢獻者: | 醫學院醫學系微生物學科;China Med Univ, Sch Med, Dept Microbiol, Taichung 404, Taiwan;China Med Univ, Sch Chinese Med, Taichung, Taiwan;Natl Taiwan Univ, Sch Med, Dept Physiol, Taipei, Taiwan;China Med Univ, Sch Pharm, Taichung, Taiwan;Natl Taiwan Univ, Coll Med, Grad Inst Clin Med, Taipei 10018, Taiwan |
| 日期: | 2003 |
| 上傳時間: | 2010-09-24 15:01:22 (UTC+8) |
| 出版者: | PERGAMON-ELSEVIER SCIENCE LTD |
| 摘要: | The main purpose of the study was to evaluate the utility of technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography (Tc-99m sestamibi SPECT) in detection of cardiac involvement in systemic lupus erythematosus (SLE) or systemic sclerosis (SS) patients. Fifty SLE or SS female patients with cardiac symptom/sign such as chest discomfort and/or dyspnea and/or occasionally palpitation and 50 SLE or SS female patients without any cardiac symptom/sign were investigated using Tc-99m sestamibi SPECT during rest and stress after dipyridamole infusion. Twenty-five age- and sex-matched healthy females were also included as controls in this study. The results of Tc-99m sestamibi SPECT were classified into four types including normal, persistent perfusion defect (PD), reversible perfusion defect (RD), and reverse perfusion defect (RR). The results of Tc-99m sestamibi SPECT in the 25 healthy females were normal. Perfusion abnormalities were detected in 44/50 (88%) symptomatic SLE or SS patients. However, myocardial perfusion abnormalities were only detected in 19/50 (38%) asymptomatic SLE or SS patients (P value < 0.05 by a chi(2) test). However, for risk factor of coronary artery disease and abnormal resting EKG, the incidences were not significant between symptomatic and asymptomatic patients (P values > 0.05 by a chi(2) test). Tc-99m sestamibi SPECT is a useful noninvasive imaging modality to detect cardiac involvement in symptomatic or asymptomatic SLE or SS patients. (C) 2003 Elsevier Ireland Ltd. All rights reserved. |
| 關聯: | LIFE SCIENCES 74(6):743-756 |
| 顯示於類別: | [醫學系] 期刊論文
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